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          劉建成
          發(fā)布時(shí)間：2024-03-22
          
				  
          
					




           

          		姓    名：劉建成

          		職    稱：特聘教授（碩士生導(dǎo)師）

          		辦公電話：  

          		電子郵箱：liujiancheng@htu.edu.cn








          個(gè)人簡(jiǎn)介：
          劉建成，博士，先后于河南師范大學(xué)生命科學(xué)學(xué)院生物技術(shù)專業(yè)（本科）、中國(guó)科學(xué)院遺傳與發(fā)育生物學(xué)研究所遺傳學(xué)專業(yè)（碩士）及發(fā)育生物學(xué)專業(yè)（博士）學(xué)習(xí)；博士畢業(yè)后于美國(guó)希望之城貝克曼研究所（Beckman Research Institute of City of Hope）進(jìn)行博士后研究，后晉升為研究員（Staff Scientist），2023年回河南師范大學(xué)工作。研究方向?yàn)榇竽X皮質(zhì)發(fā)育及神經(jīng)干細(xì)胞分化調(diào)控，研究成果發(fā)表在Development、Cerebral Cortex、Cell Reports、Science Advances、Nature Communications等頂級(jí)學(xué)術(shù)期刊。
          研究領(lǐng)域：
          神經(jīng)干細(xì)胞分化的表觀遺傳調(diào)控；
          神經(jīng)膠質(zhì)細(xì)胞的早期分化及調(diào)控；
          神經(jīng)損傷及修復(fù)再生。
          主要學(xué)術(shù)及社會(huì)兼職：
             
          主持或參加科研項(xiàng)目情況：

          學(xué)術(shù)成果：
          代表性論文： 
          1. Jiancheng Liu, Xiwei Wu, Qiang Lu. Molecular Divergence of Mammalian Astrocyte Progenitor Cells at Early Gliogenesis. Development. 2022 Mar 1;149(5):dev199985.
          2. Jiancheng Liu, Anqi Geng, Xiwei Wu, Ren-Jang Lin, Qiang Lu. Alternative RNA Splicing Associated with Mammalian Neuronal Differentiation. Cerebral Cortex. 2018 Aug1;28(8):2810-2816.
          3. JianchengLiu, Xiwei Wu, Heying Zhang, Gerd P Pfeifer, Qiang Lu. Dynamics of RNA Polymerase IIPausing and Bivalent Histone H3 Methylation during Neuronal Differentiation in Brain Development. Cell Reports.2017 Aug 8;20(6):1307-1318.
          4. JianchengLiu, Xiwei Wu, Heying Zhang, Runxiang Qiu, Kazuaki Yoshikawa, Qiang Lu. Prospective separation and transcriptome analyses of cortical projection neurons and interneurons based on lineage tracing by Tbr2 (Eomes)-GFP/Dcx-mRFP reporters. Developmental Neurobiology.2016 Jun;76(6):587-99.
          5. RunxiangQiu, Anqi Geng, Jiancheng Liu, C Wilson Xu, Manoj B Menon,Matthias Gaestel, Qiang Lu. SEPT7 Interacts with KIF20A and Regulates the Proliferative State of Neural Progenitor Cells During Cortical Development. Cerebral Cortex. 2020 May14;30(5):3030-3043.
          6. Maria AHahn, Seung-Gi Jin, Arthur X Li, Jiancheng Liu, Zhijun Huang, Xiwei Wu, Byung-Wook Kim, Jennifer Johnson, Adrienne-Denise V Bilbao, Shu Tao, Jacob A Yim, Yuman Fong, Sandra Goebbels, Markus H Schwab, Qiang Lu, Gerd PPfeifer. Reprogramming of DNA methylation at NEUROD2- bound sequences during cortical neuron differentiation. Science Advances. 2019 Oct23;5(10):eaax0080.
          7. Anqi Geng, Runxiang Qiu, Kiyohito Murai, Jiancheng Liu, Xiwei Wu, Heying Zhang, Henry Farhoodi, Nam Duong, Meisheng Jiang, Jiing-Kuan Yee, WalterTsark, Qiang Lu. KIF20A/MKLP2 regulates the division modes of neural progenitor cells during cortical development. Nature Communications. 2018 Jul13;9(1):2707.
          8. Lu Yang, Jiancheng Liu,Qiang Lu, Arthur D Riggs, Xiwei Wu. SAIC: an iterative clustering approach for analysis of single cell RNA-seq data. BMC Genomics. 2017 Oct3;18(Suppl 6):689.
          9. Seung-GiJin, Zhi-Min Zhang, Thomas L Dunwell, Matthew R Harter, Xiwei Wu, Jennifer Johnson, Zheng Li, Jiancheng Liu, Piroska E Szabo?, Qiang Lu, Guo-Liang Xu, Jikui Song, Gerd P Pfeifer. Tet3 Reads 5-Carboxylcytosine through Its CXXC Domain and Is a Potential Guardian against Neurodegeneration. Cell Reports. 2016 Jan 26;14(3):493-505.
          10. Fang Chen, Wei Zhang, Yu Liang, Jialiang Huang, Kui Li, Christopher D Green, Jiancheng Liu, Guojie Zhang, Bing Zhou, Xin Yi, Wei Wang, Hang Liu, Xiaohong Xu, Feng Shen, Ning Qu, Yading Wang, Guoyi Gao, A San, Luo Sang Jiang Bai, Hua Sang, Xiangdong Fang, Karsten Kristiansen, Huanming Yang, Jun Wang, Jing-Dong J Han, Jian Wang. Transcriptome and Network Changes in Climbers at Extreme Altitudes. PLoS One. 2012;7(2):e31645.
          11. Chunyu Jin, Jing Li, Christopher D Green, Xiaoming Yu, Xia Tang, Dali Han, Bo Xian,Dan Wang, Xinxin Huang, Xiongwen Cao, Zheng Yan, Lei Hou, Jiancheng Liu, Nicholas Shukeir, Philipp Khaitovich, Charlie D Chen, Hong Zhang, Thomas Jenuwein, Jing-Dong J Han. Histone Demethylase UTX-1 Regulates C. elegans Life Span by Targeting the Insulin/IGF-1 Signaling Pathway. Cell Metabolism. 2011 Aug3;14(2):161-72.
          12. Jiancheng Liu, Like Liu, Ning Hou, Aimin Zhang, Chunguang Liu. Genetic Diversity of Wheat Gene Pool of Recurrent Selection Assessed by Microsatellite Markers and Morphological Traits. Euphytica. 2006 Dec 21;155: 249-258.
          13. Chunguang Liu, Ning Hou, Like Liu, Jiancheng Liu, Xusheng Kang and Aimin Zhang. A YA-type cytoplasmic male-sterile source in common wheat. Plant Breeding.2006 Sep12;125, 437-440.