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          辛鵬洋

          辛鵬洋



          辛鵬洋,博士,副教授,碩士生導(dǎo)師


          河南省優(yōu)秀青年科學(xué)基金獲得者(2021年入選)

          E-Mail:pyxin27@163.com   



          教育與研究經(jīng)歷:

          2019.2-至 今   河南師范大學(xué)      化學(xué)化工學(xué)院   副教授

          2015.7-2019.1   河南師范大學(xué)      化學(xué)化工學(xué)院   講師

          2012.9-2015.6   復(fù) 旦 大 學(xué)      獲博士學(xué)位

          2009.9-2012.6   河南師范大學(xué)      獲碩士學(xué)位

          2005.9-2009.6   許 昌 學(xué) 院     獲學(xué)士學(xué)位

            

          研究領(lǐng)域與興趣:

          超分子化學(xué)、化學(xué)生物學(xué)。構(gòu)建有機(jī)超分子體系模擬生物大分子的結(jié)構(gòu)與功能,并進(jìn)一步研究其在生物醫(yī)藥方面的潛在應(yīng)用,Acc. Chem. Res., J. Am. Chem. Soc., Angew. Chem. Int. Ed., Green Chem.以及Chem. Commun.等國內(nèi)外具有重要影響力的期刊上發(fā)表論文多篇。

            

          近年來主持的主要科研項(xiàng)目:

             1、國家自然科學(xué)基金-面上項(xiàng)目,2022,在研,主持

             2、國家自然科學(xué)基金-聯(lián)合基金,2020,在研,主持

             3、河南省高等學(xué)校重點(diǎn)科研項(xiàng)目-基礎(chǔ)研究專項(xiàng),2021,在研,主持

             4、河南師范大學(xué)國家自然科學(xué)基金面上項(xiàng)目培育項(xiàng)目,在研,主持

             5、國家自然科學(xué)基金青年基金,結(jié)項(xiàng),主持

             6、河南省2016年科技發(fā)展計(jì)劃-基礎(chǔ)與前沿技術(shù)研究,結(jié)項(xiàng),主持



          代表性論文與專利:


          1.Pengyang Xin,* Linqi Xu, Wenpei Dong, Linlin Mao, Jingjing Guo,* Jingjing Bi, Shouwei Zhang, Yan Pei, Chang-Po 

             Chen*, Synthetic K+ Channels Constructed by Rebuilding the Core Modules of Natural K+ Channels in an Artificial 

             System. Angew. Chem. Int. Ed.2023e202217859. (Hot Paper,  通訊作者,IF = 16.823)




          2. Pengyang Xin,* Lingyu Zhao, Linlin Mao, Linqi Xu, Shuaimin Hou, Huiyuan Kong, Haodong Fang, Haofeng Zhu, Tao Jiang, Chang-Po Chen*, Effect of Charge Status on the Ion Transport and Antimicrobial Activity of Synthetic Channels. Chem. Commun.,2020,DOI: 10.1039/D0CC05730D.(通訊作者,IF = 5.996)

            

            

          3. Pengyang Xin,* Huiyuan Kong, Yonghui Sun, Lingyu Zhao, Haodong Fang, Haofeng Zhu, Tao Jiang, Jingjing Guo, Qian Zhang, Wenpei Dong, Chang-Po Chen*,Artificial K+Channels Formed by Pillararene-Cyclodextrin Hybrid  Molecules: Tuning Cation Selectivity and Generating Membrane Potential,Angew. Chem. Int. Ed.,2019,58, 2779-2784.(通訊作者,IF = 12.102)

          4. Pengyang Xin,* Si Tan, Yaodong Wang, Yonghui Sun, Yan Wang, Yuqing Xu andChang-Po Chen*,Functionalized hydrazide macrocycle ion channels showing pH-sensitive ion selectivities,Chem. Commun.,2017,53, 625-628.

              (通訊作者,IF = 6.319)

          5.  Pengyang Xin,* Si Tan, Yonghui Sun, Qiaojv Ren, Wenpei Dong, Jingjing Guo, Tao Jiang and Chang-Po Chen,*

              One-pot formation of hydrazide macrocycles with modified cavities: an example of pH-sensitive unimolecular cation channels,Chem. Commun.,2017,53, 5322-5325.(通訊作者,IF = 6.319)

          6. Pengyang Xin,* Yonghui Sun, Huiyuan Kong, Yaodong Wang, Si Tan, Jingjing Guo, Tao Jiang, Wenpei Dong* and Chang-Po Chen*,A unimolecular channel formed by dual helical peptide modified pillar[5]arene: correlating transmembrane transport properties with antimicrobial activity and haemolytic toxicity,Chem. Commun.,2017,53, 11492-11495. (通訊作者,IF = 6.319)

          7. Min Zhang, Ping-Ping Zhu ,Pengyang Xin, Wen Si, Zhan-Ting Li, and Jun-Li Hou*,Synthetic Channel Specifically  Inserts into the Lipid Bilayer of GramPositive Bacteria but not that of Mammalian Erythrocytes,Angew. Chem. Int. Ed.,2017,56, 2999-3003. (IF = 11.994)

            

          8. Lingjun Li* , Qianqian Li, Shengqiang Ding,Pengyang Xin, Yuqin Zhang, Shenlong Huang and Guisheng Zhang*,  ADP-ribosyl-N3: A Versatile Precursor for Divergent Syntheses of ADP-ribosylated Compounds,Molecules,2017,22, 1346.   (IF = 2.861)

            

          9.  Pengyang Xin,PingpingZhu, Pei Su, Jun-Li Hou* and Zhan-Ting Li*,Hydrogen-Bonded Helical Hydrazide Oligomer and Polymer That Mimic the Ion Transport of Gramicidin A,J. Am. Chem. Soc.,2014,136, 13078-13081.

             (第一作者,IF = 12.113)

          10. Pengyang Xin, Liang Zhang, Pei Su, Jun-Li Hou* and Zhan-Ting Li*,Hydrazide macrocycles as effective transmembrane channels for ammonium.Chem. Commun.,2015, 47,11140-11142.(第一作者,IF = 6.834)

            

          11.  Peng-Yang Xin, Hong-Ying Niu, Gui-Rong Qu* Rui-Fang Ding, Hai-Ming Guo*,Nickel catalyzed alkylation of N-aromatic heterocycles with Grignard reagents through direct C–H bond functionalization.Chem. Commun.,2012,48,  6717-  6719. (第一作者,IF = 6.834)

          12. Gui-Rong Qu,*Peng-Yang Xin,Hong-Ying Niu, Dong-Chao Wang, Rui-Fang Ding, Hai-Ming Guo*,Nickel-catalyzed sp2C–H bonds arylation of N-aromatic heterocycles with Grignard reagents at room temperature.Chem. Commun.,2011,47,11140-11142.(除導(dǎo)師外第一作者,IF = 6.834)

          13.Hai-Ming Guo,*Peng-Yang Xin, Hong-Ying Niu, Gui-Rong Qu*,Microwave irradiated C6-functionalization of 6-chloropurine nucleosides with various mild nucleophiles under solvent-free conditions.Green Chem.,2010,12, 2131-2134.(除導(dǎo)師外第一作者,IF = 8.02)

          14.Gui-Rong Qu,*Peng-Yang Xin,  Hong-Ying Niu,Hai-Ming Guo,*Microwave promoted palladium-catalyzed Suzuki-Miyaura cross-coupling reactions of 6-chloropurines with sodium tetraarylborate in water.Tetrahedron,2011,67,9099-    9103. (除導(dǎo)師外第一作者,IF = 2.803)

          15.Yingtang Zhang,*Pengyang Xin,*Qiufeng Yao,Electrochemical performance of LiFePO4/C synthesized by sol-gel method as cathode for aqueous lithium ion batteries.J. Alloy. Compd.,2018,74,404-408(通訊作者,IF = 3.779)

          16.Wen Si,Pengyang Xin,Zhan-Ting Li, Jun-Li Hou,*Tubular UnimolecularArtificial Transmembrane Channels:Construction Strategies and Transport Activities.Acc. Chem. Res.,2015,48,1612-1619. (IF = 22.323)

          17.Qian Zhang,*Chun-Hang Zhang,Jun-Hui Yang,Peng-Yang Xin,Xiao-Peng Xuan,Jian-Ge Wang,Na-Na Ma,Hai-MingGuo andGui-Rong Qu,A four-unit [c2]daisy chain connected by hydrogen bonds.Chem. Commun.,2015,51, 15253-15256.(IF = 6.834)

          18.Yu-Qin Jiang, Kai Wu, Qian Zhang, * Ke-Qing Li, Yan-Yan Li,Peng-Yang Xin, Wei-Wei Zhang and Hai-Ming Guo*,A dual-responsive hyperbranched supramolecular polymer constructed by cooperative host–guest recognition and hydrogen-bond interactions.Chem. Commun.,2018,54, 13821-13824.(IF = 6.834)  

          19.辛鵬洋,牛紅英,渠桂榮,楊西寧,郭海明,*四芳基硼鈉的簡便合成.合成化學(xué),2011,19,671-672.

          20.祝平平,辛鵬洋,侯軍利*,黎占亭*,乙酰膽堿經(jīng)人工通道的跨膜輸送.Chin. J. Org. Chem.,2015,35, 1994-1998.

          21.祝平平,辛鵬洋,侯軍利*,黎占亭*,間苯二甲酸自組裝形成的人工跨膜離子通道.中國科學(xué):化學(xué),2015,45,624-628.

          22.郭海明*,李璞,辛鵬洋,王東超,牛紅英,渠桂榮*,微波促進(jìn)的6-位磷功能化的非環(huán)嘌呤核苷類似物的合成.中國科學(xué):化學(xué),2010,40, 963-966.




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