王文晟，博士，河南師范大學(xué)特聘教授，博士生導(dǎo)師，2000年畢業(yè)于日本東京大學(xué)藥學(xué)院，獲藥學(xué)博士學(xué)位。畢業(yè)后作為特別研究員在日本國(guó)立食品藥品衛(wèi)生研究所(NIHS)工作，從事與DNA的復(fù)制，修復(fù)和同源重組相關(guān)的罕見(jiàn)遺傳病（Bloom syndrome, Werner syndrome等）的研究。后轉(zhuǎn)到美國(guó)加州大學(xué)，羅切斯特大學(xué)從事DNA的復(fù)制，修復(fù)和同源重組，及自免疫疾病方面的研究工作。2016年回國(guó)，被新鄉(xiāng)醫(yī)學(xué)院聘為特聘教授?，F(xiàn)作為特聘教授到河南師范大學(xué)生命科學(xué)學(xué)院工作。近年來(lái)在國(guó)家自然科學(xué)基金和美國(guó)健康衛(wèi)生研究所的資助下從事與神經(jīng)精神性疾?。ㄒ钟舭Y）和骨相關(guān)疾病（如溶骨病和骨關(guān)節(jié)炎）方面的研究。在國(guó)際權(quán)威期刊發(fā)表SCI論文28篇。

    骨生物學(xué)，神經(jīng)生物學(xué)，主要從事神經(jīng)精神性疾病，骨關(guān)節(jié)炎和溶骨病的研究。

無(wú)

1.國(guó)家自然科學(xué)基金面上項(xiàng)目，淋巴內(nèi)皮細(xì)胞來(lái)源的Sema3A在戈勒姆綜合癥發(fā)病中的作用和機(jī)制 (81974321)，2020/01-2023/12，60萬(wàn)元，在研，主持

2. 河南省自然科學(xué)基金，162300410217，可用于抑郁癥診斷的標(biāo)示microRNA的篩選和其作用機(jī)制的探討，2017/01-2018/12，10萬(wàn)元，結(jié)題，主持

代表性論文：    

1. Wang Wensheng, Lin X, Xu H, Sun W, Bouta EM, Zuscik MJ, Chen D, Schwarz EM, Xing L. Attenuated JointTissue Damage Associated With Improved Synovial Lymphatic Function FollowingTreatment With Bortezomib in a Mouse Model of Experimental PosttraumaticOsteoarthritis. Arthritis Rheumatol. 2019Feb;71(2):244-257. (一區(qū)，IF=9.002)

2. Wang Wensheng, Wang H, Zhou X, Li X, Sun W, DellingerM, Boyce BF, Xing L.Lymphaticendothelial cells produce M-CSF causing massive bone loss in mice. Journal of bone and mineral research.2017 May; 32(5): 939-950.（一區(qū)，IF=6.314）

3. Chao-Zhi Tang, Dong-Fang Zhang, Jun-Tang Yang, Qing-Hui Liu, Ya-Ru Wang, and Wen-Sheng Wang*.Overexpression of microRNA-301b accelerates hippocampal microglia activationand cognitive impairment in mice with depressive-like behavior through theNF-κB signaling pathway. Cell Death Dis.2019 Apr; 10(4): 316. (二區(qū)，IF=5.959)  *通訊作者

4. Chao-ZhiTang, Jun-TangYang, Qing-HuiLiu, Ya-Ru Wang, Wen-ShengWang*. Up-regulated miR-192-5p expressionrescues cognitive impairment and restores neural function in mice withdepression via the Fbln2-mediated TGF-β1 signalingpathway. FASEB J. 2019 Jan;33(1):606-618. (二區(qū)，IF=5.391) *通訊作者

5. TangChaozhi, Zhang Yuling, Wang Wensheng*,Li Weiguo, Shi Jipeng. Serum levels of high-sensitivity C-reactive protein atadmission are more strongly associated with post stroke depression in acuteischemic stroke than homocysteine levels [J]. Molecular Neurobiology. 2016; 53(4):2152-60.（二區(qū)，IF=6.19）*通訊作者

6. TangChaozhi, Zhang Yuling, Wang Wensheng*,Li Weiguo, Shi Jipeng. Elevated serum levels of neopterin at admission predictsdepression after acute ischemic stroke: A 6-month follow-up study [J]. Molecular Neurobiology. 2016 July;53(5):3194-204.（二區(qū)，IF=6.19）*通訊作者

7. Tang Chaozhi, Zhang Yuling, Shi Jipeng. Wang Wensheng*, Liang Le, . The complete mitochondrial genomeof Bos gaurus gon-shan (Bovidae; Bovinae).MitochondrialDNA.2016; 27(2):1050-1. (四區(qū)，IF=3.35）*通訊作者

8. Wensheng Wang, Javier Rangel-Moreno, Teresa Owena, JenniferBarnarda, Travis Ichikawaa, and Jennifer H. Anolik. Long-term B cell depletion in murine lupus eliminatesautoantibody-secreting cells by altering the plasma cell niche.  J Immunol. 2014; 192(7): 3011-20. （二區(qū)，IF=5.362）

9. Chiu YH, SchwarzE, Li D, Xu Y, Sheu TR, Li J, Bentley KL, Feng C, Wang B, Wang JC,Albertorio-Saez L, Wood R, Kim M, Wang Wensheng, Ritchlin CT.  Dendritic Cell-Specific Transmembrane Protein (DC-STAMP) RegulatesOsteoclast Differentiation via the Ca2+ /NFATc1 Axis.  J Cell Physiol. 2017; 232: 2538–2549(二區(qū)，IF=4.155)

10. Qianqian Liang,Yawen Ju,Yan Chen,Wensheng Wang,Jinlong Li,Li Zhang,Hao Xu,Ronald W. Wood,Edward. M. Schwarz,Brendan F. Boyce,Yongjun Wang andLianping Xing. Lymphaticendothelial cells efferent to inflamed joints produce iNOS and inhibitlymphatic vessel contraction and drainage in TNF-induced arthritis in mice. Arthritis Res Ther.2016;18:62.  (二區(qū)，IF=3.979)

11. Diana Adlowitz, JenniferHossler, Jamie Biear, Christopher Cistrone, Teresa Owen, Wensheng Wang, Arumugam Palanichamy, Ezinma Ezealah, DebbieCampbell, Chungwen Wei, R. John Looney, Inaki Sanz, and Jennifer H.Anolik.  Expansion of activated memory Bcells in RA and impact of B cell depletion therapy.  PLoS One. 2015; 10(6). （二區(qū)，IF=3.53）