代表性論文 Wang L,Wang Y, Dong Z*, Chen G*, Sluy R, and Liu D. Integrative taxonomy a new speciesof Dugesia (Platyhelminthes, Tricladida, Dugesiidae) from unveils the southern portion of the Taihang Mountains in northern China, with the description of itscomplete mitogenome and an exploratory analysis of mitochondrial gene order asa taxonomic character. Integrative Zoology, 2021,0:1-22. Zimei Dong, Jinrui Huo, Ang Liang, Jinzi Chen, Guangwen Chen?, Dezeng Liu. Gamma-Secretase Inhibitor (DAPT), a potentialtherapeutic target drug,caused neurotoxicity in planarian regeneration by inhibiting Notch signaling pathway. Scienceof the Total Environment, 2021,781,146735. Lei Wang, Zi-mei Dong, Guang-wen Chen ?, Ronald Sluys, De-zeng Liu.Integrative descriptions of two new species of Dugesiafrom Hainan Island, China (Platyhelminthes, Tricladida, Dugesiidae). ZooKeys, 2021,1028:1–28. WangL, Chen J, Dong Z*, Chen G*, Sluy R, and Liu D. Two new species of Dugesia(Platyhelminthes, Tricladida, Dugesiidae) from the tropical monsoon forest insouthern China. ZooKeys , 2021,1059: 89-116. YiboYang, Peizheng Wang, Baijie Jin, Zimei Dong, Guangwen Chen ?,Dezeng Liu. Screening of Potential Key Transcripts Involved in PlanarianRegeneration and Analysis of Its Regeneration Patterns by PacBio Long-Read Sequencing.Front Genet, 2020,11: 580. Xueqiang Guo,Lingling Xi, Lifei Li, Jianlin Guo, Wei Jin, Cuifang Chang, Jingbo Zhang,Cunshuan Xu, Guangwen Chen*，circRNA-14723 promotes hepatocytes proliferation in rat liver regeneration by sponging rno-miR-16-5p.Journal Celluar Physiology,2020,29473. Zimei Dong, Fangfang Cheng, Yibo Yang, Fenxi Zhang, Guangwen Chen?, Dezeng Liu. Expression and functional analysis of flotillins in Dugesia japonica. Experimental Cell Research, 2019, 374:76-84. Fenxi Zhang, Zimei Dong,Shuai Gao, Guangwen Chen?, and Dezeng Liu. AT1R-Mediated Apoptosis of Bone Marrow Mesenchymal Stem Cells Is Associated with mtROS Production and mtDNA Reduction. Oxidative Medicine and Cellular Longevity, 2019, 4608165:1-9. Jing Kang, Zimei Dong, QinHao, Jing Wang, Guangwen Chena?, Dezeng Liu.The regulation of rapamycin in planarian Dugesia japonica Ichikawa & Kawakatsu, 1964 regeneration according to TOR signaling pathway. Ecotoxicology and Environmental Safety, 2019, 185:1-8 Zhang HC, Ma KX, Yang YJ, Shi CY, Chen GW?, Liu DZ. CuZnSOD and MnSOD from freshwater planarian Dugesia japonica: cDNA cloning, mRNA expression and enzyme activity in response to environmental pollutants. Aquat Toxicol, 2019, 208:12-19. Ke-Xue Ma, Ge-ge Song, MengWu, He-Cai Zhang, Guang-Wen Chen?, De-Zeng Liu.Identificationof a potential tissue-specific biomarker cathepsin L-like gene from the planarian Dugesia japonica: Molecular cloning, characterization, and expressionin response to heavy metal exposure. Ecotoxicology and Environmental Safety,2019,180: 73-79. Kexue Ma, Yumei Zhang, Gege Song, Meng Wu and Guangwen Chen?.Identification of Autophagy-Related Gene 7 and Autophagic Cell Death in the Planarian Dugesia japonica.FRONTIERS IN PHYSIOLOGY,2018,9:1-10. Zhang HC, Ma KX, Yang YJ,Shi CY, Chen GW?, Liu DZ. Molecular cloning, characterization, expression and enzyme activityof Catalase from planrian Dugesia japonica in response to environmental pollutants. Ecotoxicology and Environmental Safety, 2018,165: 88-95. BaijieJin, Jing Ren, Jinzi Chen, Zimei Dong*, Guangwen Chen*, Dezeng Liu.Autophagy?related DjAtg1?1 plays critical role in planarian regeneration by regulating proliferation and cell death. Cell and Tissue Research, 2022, doi.org/10.1007/s00441-022-03591-3. Qinghua Wang, Lijuan Xie, Yixuan Wang, Baijie Jin, Jing Ren, Zimei Dong *,Guangwen Chen *, Dezeng Liu. Djhsp70s, especially Djhsp70c, play a key role in planarian regeneration and tissue homeostasis by regulating cell proliferation and apoptosis. Gene, 2022, 820 : 146215. Yingyu Liu, Jinzi Chen, Zimei Dong ?, Guangwen Chen ?, Dezeng Liu. Antioxidant responses and lipidperoxidation can be used as sensitive indicators for the heavy metals risk assessment of the Wei River: a case study of planarian Dugesia Japonica.Biomarkers, 2021:26: 55-64. Qinghua Wang, Yingyu Liu, Baijie Jin, Zimei Dong*, Guangwen Chen*, Dezeng Liu. Djmek is involved inplanarian regeneration by regulation of cell proliferation and apoptosis.Biochemical and Biophysical Research Communications,2020, 532:355-361. He-Cai Zhang, Yu-Juan Yang, Ke-Xue Ma, Chang-Ying Shi, Guang-Wen Chen ?, De-Zeng Liu.A novel sigma classglutathione S-transferase gene in freshwater planarian Dugesia japonica:cloning, characterization and protective effects in herbicide glyphosate stress.Ecotoxicology, 2020, 29:295–304. He?Cai Zhang, Chang?Ying Shi, Yu?Juan Yang, Guang?Wen Chen?, De?ZengLiu. Biomarkers of Planarian Dugesia japonica in Response to Herbicide Glyphosate Exposure. Bulletin of Environmental Contamination and Toxicology,2020, 104:804–808. Zimei Dong, Gengbo Chu, Yingxu Sima, Guangwen Chen*. Djhsp90s are crucial regulators during planarianre generation and tissue homeostasis.Biochemical and Biophysical Research Communications, 2018, 498:723-728. Zimei Dong, Yibo Yang, Guangwen Chen?, Dezeng Liu. Identification of runt family genes involved in planarian regeneration and tissue homeostasis. Gene Expression Patterns,2018,29:24-31. Zimei Dong, Changying Shi, Gengbo Chu, Yanping Dong, Guangwen Chen?, Dezeng Liu. Morphological changes of gonad and gene expression patterns during desexualization in Dugesia japonica (Platyhelminthes:Dugesiidae). Zoologia (Curitiba),2018, 35:1-7. HeCai Zhang, ChangYing Shi, HuiHui Yang, GuangWen Chen? , DeZeng Liu. Genotoxicity evaluation of ionic liquid 1-octyl-3-methylimidazolium bromide in freshwater planarian Dugesia japonica using RAPD assay. Ecotoxicology and Environmental Safety, 2016,134:17-22. Zimei Dong, Yanqing Yuwen, Qinghua Wang,Guangwen Chen?, Dezeng Liu. The characteristics of sox gene in Dugesia japonica. Mol Biol Rep,2011,38:3977-82. Zimei Dong, Yanqing Yuwen, Qinghua Wang, Guangwen Chen?, Dezeng Liu. Eight genes expression patterns during visual systemre generation in Dugesia japonica. Gene Expression Patterns, 2012,12:1-6. Zimei Dong, Changying Shi, Haixia Zhang, HeDou, Fangfang Cheng, Guangwen Chen?, Dezeng Liu. The characteristics of sox gene in Dugesia japonica. Gene, 2014,544:177-183. Fangfang Cheng, Zimei Dong, Yanping Dong, Yingxu Sima, Jing Chen, Xiaoyan Li, Guangwen Chen?, Dezeng Liu.Identification and expression analysis of a heat shock protein 70 gene in Polycelis sp. Cell Stress and Chaperones, 2015, 20:907-915. Zimei Dong, Fangfang Cheng, Yanqing Yuwen, Jing Chen, Xiaoyan Li, He Dou, Haixia Zhang, Guangwen Chen?, Dezeng Liu. Identification and expression analysis of a Spsb gene in planarian Dugesia japonica. Gene,2015,564:168-175. ZimeiDong, Tong Yang, Yibo Yang, He Dou, Guangwen Chen?. DjhnRNPA2/B1-like gene isrequired for planarian regeneration and tissue homeostasis. Gene,2017,633:9-16. Zimei Dong, Yanqing Yuwen, Yingxu Sima, Yanping Dong, Huina Zhan, Guangwen Chen?, Dezeng Liu. Photokinesis and Djopsin gene expression analysis during the regeneration of planarian eyes. Integrative Zoology, 2017,12:57-164. ZiMei Dong, GuangWen Chen?, HeCai Zhang, DeZeng Liu. A new species of Polycelis(Platyhelminthes, Tricladida,Planariidae) from China. Acta Zoologica Academiae Scientiarum Hungaricae, 2017,63:263-276. Yanqing Yuwen, Zimei Dong, Qinghua Wang, Xiaojuan Sun, Changying Shi, Guangwen Chen?. Evaluation of endogenous reference genes for analysis of gene expression with real-time RT-PCR duringplanarian regeneration. Mol Biol Rep,2011,38:4423–4428. Yanqing Yuwen, Zimei Dong, Xiaohui Si, Guangwen Chen?. A pumilio homolog in Polycelis sp. Dev Genes Evol, 2014,224:53–56. HeCai Zhang, ChangYing Shi, LiQun Sun, FanWang, GuangWen Chen?.Toxic effects of ionic liquid1-octyl-3-methylimidazolium bromide on the antioxidant defense system offreshwater planarian, Dugesia japonica.Toxicology and Industrial Health, 2016, 32:1675–1683. HeCai Zhang, ChangYing Shi, Fan Wang,GuangWen Chen?, DeZeng Liu. Imidazolium-based ionic liquids: Effects of different alkyl-chain lengths on planarian Dugesia Japonica based on ingestion, regeneration and antioxidant response. Fresenius Environmental Bulletin,2016,25:3205-3212. HeCai Zhang, TongYi Liu, ChangYing Shi, GuangWen Chen?, DeZeng Liu. Genotoxicity evaluation of an urban river on freshwater planarian by RAPD assay. Bull Environ Contam Toxicol, 2017,98:484–488. Changying Shi, Zimei Dong, Hecai Zhang, Fangfang Cheng, Guangwen Chen?, Dezeng Liu. Cloning and characterization of DjPRPS gene in freshwater planarian Dugesia japonica. Turkish Journal of Biochemistry, 2015,40:58–65. ChangYing Shi, HeCai Zhang, GuangWen Chen?, LiQun Sun, DeZeng Liu. Toxicity of ionic liquid 1-octyl-3-methylimidazolium bromide on freshwater planarian, Dugesia Japonica. Fresenius Environmental Bulletin, 2013, 22:1609 -1615. Hecai Zhang, Guangwen Chen?, Xiaojuan Sun, CunshuanXu. Study on phylogenetic relationship of freshwater planarians (Turbellaria:Tricladida: Paludicola) in nine Chinese localities using RAPD method. Life Science Journal,2009,16:71-75. KeXue Ma, GuangWen Chen?, DeZeng Liu. cDNA cloningof heat shock protein 90 gene and protein expression pattern in response toheavy metal exposure and thermal stress in planarian Dugesia japonica. Mol Biol Rep, 2012,39:7203–7210. GuangWen Chen?, KeXue Ma DeZeng Liu.Changes of alkaline phosphatase activity in response to different stressors inplanarian Dugesia japonica. Biologia,2013,68:264-268. KeXue Ma, GuangWen Chen?, Hao Lou, LiNa Fei.Cloning and expression analysis of hsp70 gene from freshwater planarian Dugesia japonica. Biologia,2009,64:1018-1024. KeXue Ma, GuangWen Chen?, ChangYing Shi, FangFang Cheng, He Dou, ChengCheng Feng, DeZeng Liu. Molecular characterization of theglucose-regulated protein 78 (GRP78)gene in planarian Dugesia japonica. Comparative Biochemistry and Physiology, Part B,2014,171:12-17. Kexue Ma, Hecai Zhang, Yumei Zhang, Gege Song, Meng Wu, Guangwen Chen? Identification of a HSP40 gene involved inplanarian regeneration. Biologia,2017,72（11）: 1-8. Xiaofang Geng, Gaiping Wang, Yanli Qin,Xiayan Zang, Pengfei Li, Zhi Geng, Deming Xue, Zimei Dong, Kexue Ma, GuangwenChen?,Cunshuan Xu?. iTRAQ-based quantitative proteomic analysis of the initiation of head regeneration in planarians. 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專利成果： 寧黔冀，楊洪，程鴻軒，陳廣文. 保幼激素拮抗物溶液及用其提高水產(chǎn)養(yǎng)殖甲殼動(dòng)物成活率方法.2008年獲國(guó)家發(fā)明專利（專利號(hào)ZL200510017350.X）.
專著教材： 汪松，解焱，劉瑞玉，宋大祥，趙爾宓，李振宇，伍漢霖，武云飛，何芬奇，丁長(zhǎng)青，周江，陳又生，劉月英，吳岷，袁德成，武春生，楊親二，耿玉英，費(fèi)梁，劉惠寧，楊思涼，Ohler Annemarie, William Bleisch, 陳輩樂，陳廣文（負(fù)責(zé)淡水渦蟲部分）等112位專家,《中國(guó)物種紅色名錄--第一卷：紅色名錄》,北京,高等教育出版社，2004年8月. 汪松，解焱，劉瑞玉，宋大祥，劉月英，吳岷，袁德成，武春生，楊思涼，陳廣文（負(fù)責(zé)淡水渦蟲部分）等30位專家,《中國(guó)物種紅色名錄--第三卷：無脊椎動(dòng)物》,北京,高等教育出版社，2005年7月. 陳廣文（負(fù)責(zé)淡水渦蟲部分）等. 《中國(guó)大百科全書》（第二版），2：365, 北京,中國(guó)大百科全書出版社，2009年3月. 陳廣文（負(fù)責(zé)淡水渦蟲部分）等, 《中國(guó)大百科全書》（第二版），18：474. 北京,中國(guó)大百科全書出版社，2009年3月. 陳廣文（負(fù)責(zé)淡水渦蟲部分）等, 《中國(guó)大百科全書》（第二版），29： 286, 北京,中國(guó)大百科全書出版社，2009年3月. 陳廣文，李仲輝主編,《動(dòng)物學(xué)實(shí)驗(yàn)技術(shù)》,北京,科學(xué)出版社，2008年2月.
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