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          教授
          當(dāng)前位置：首頁  師資隊伍  教師名錄  生物科學(xué)系  教授
          
			
          
		
          
			
          
				
				 
          董自梅
          發(fā)布時間：2022-03-07
          
				  
          
					





          		姓   名：董自梅

          		職   稱：教授 博士生導(dǎo)師

          		辦公電話：0373-3326340

          		電子郵箱：dzmhjx@163.com








          個人簡介：
          1992年畢業(yè)于河南師范大學(xué)動物學(xué)專業(yè)，獲學(xué)士學(xué)位，2011年獲河南師范大學(xué)生命科學(xué)學(xué)院動物學(xué)專業(yè)博士學(xué)位。長期從事動物資源保護與利用及神經(jīng)再生機制的研究，主持國家自然科學(xué)基金面上項目3項，主持完成河南省重點科技攻關(guān)項目1項，河南省自然科學(xué)基金項目2項，河南省教學(xué)改革項目1項；參與國家自然科學(xué)基金面上項目3項，河南重大公益項目1項。河南省高等學(xué)校創(chuàng)新團隊主持人。在國內(nèi)外重要學(xué)術(shù)期刊發(fā)表論文60多篇，獲得國家教學(xué)成果二等獎1項，河南省高等教育教學(xué)成果一等獎1項，獲河南省自然科學(xué)優(yōu)秀論文一等獎3項。參編的《普通動物學(xué)》、《動物學(xué)實驗技術(shù)》2部教材被評為省級規(guī)劃教材。主講《普通動物學(xué)》、《醫(yī)學(xué)寄生蟲學(xué)》、《分子生態(tài)學(xué)》和《動物發(fā)育及再生生物學(xué)》等本科及研究生課程。
          研究領(lǐng)域：
              動物資源保護與利用；組織再生機制研究。
          主要學(xué)術(shù)及社會兼職：
             全國動物學(xué)名詞審定委員會委員；《中國大百科全書》特邀編委；河南省動物學(xué)會理事長；河南省濮陽黃河濕地生態(tài)系統(tǒng)野外科學(xué)觀測研究站副站長。
          主持或參加科研項目情況：
          1.主持國家自然科學(xué)基金面上項目《廣東、廣西淡水渦蟲分類區(qū)系及系統(tǒng)進化研究》；
          2.主持國家自然科學(xué)基金面上項目《海南島淡水三腸目渦蟲生態(tài)學(xué)及進化生物學(xué)研究》；
          3.主持國家自然科學(xué)基金面上項目《組織再生關(guān)鍵基因的篩選及功能研究 —以日本三角渦蟲為例》；
          4.主持河南省高?？萍紕?chuàng)新團隊《中國淡水渦蟲資源及再生機制研究》；
          5.主持河南省重點科技攻關(guān)項目《淡水渦蟲神經(jīng)生長因子基因的克隆表達及應(yīng)用》；
          6.主持河南省重點教改項目《人體寄生蟲學(xué)教學(xué)內(nèi)容教學(xué)方法和教學(xué)手段的改革與實踐》；
          7.主持河南省自然科學(xué)基金項目《Sox基因家族在日本三角渦蟲中的克隆及表達分析》；
          8.主持河南省自然科學(xué)基金項目《多目渦蟲眼點再生相關(guān)基因的克隆及表達分析》；
          9.參與國家自然科學(xué)基金面上項目《秦嶺山脈淡水三腸目渦蟲分類和區(qū)系研究》；
          10.參與國家自然科學(xué)基金面上項目《云貴高原淡水渦蟲生態(tài)學(xué)及進化生物學(xué)研究》；
          11.參與國家自然科學(xué)基金面上項目《橫斷山區(qū)淡水渦蟲生態(tài)學(xué)及進化生物學(xué)研究》；
          12.參與河南省重大公益項目《黃河中下游生物多樣性保育和生態(tài)廊道建設(shè)技術(shù)集成與示范》；
          13.參與河南省重點教學(xué)改革項目《基礎(chǔ)教育生物學(xué)拔尖人才培養(yǎng)模式研究與實踐》。
          學(xué)術(shù)成果：
          代表性論文：
          1. Wang L, Wang Y, Dong Z*, Chen G*, Sluy R, and Liu D. Integrative taxonomy unveils a new species of Dugesia (Platyhelminthes, Tricladida, Dugesiidae) from the southern portion of the Taihang Mountains in northern China,with the description of its complete mitogenome and an exploratory analysis of mitochondrial gene order as a taxonomic character. Integrative Zoology, 2021, 1-22.
          2. Zimei Dong, Jinrui Huo, Ang Liang, Jinzi Chen, Guangwen Chen?, Dezeng Liu.Gamma-Secretase Inhibitor (DAPT), a potential therapeutic target drug,caused neurotoxicity in planarian regeneration by inhibiting Notch signaling pathway.Science of the Total Environment, 2021,781,146735.
          3. Wang L, Chen J, Dong Z*, Chen G*, Sluy R, and Liu D. Two new species of Dugesia (Platyhelminthes, Tricladida, Dugesiidae) from the tropical monsoon forest in southern China. ZooKeys, 2021, 1059: 89-116.
          4. Kang J, Chen J, Dong Z*, Chen G*, Liu D. The negative effect of the PI3K inhibitor 3-methyladenine on planarian regeneration via the autophagy signalling pathway. Ecotoxicology, 2021, 30(9): 1941-1948.
          5. Wang L, Dong Z, Chen G*, Sluy R, Liu D. Integrative descriptions of two new species of Dugesia from Hainan Island, China (Platyhelminthes, Tricladida, Dugesiidae). ZooKeys, 2021, 1028: 1-28.
          6. Yibo Yang, Peizheng Wang, Baijie Jin, Zimei Dong?, Guangwen Chen?, Dezeng Liu. Screening of Potential Key Transcripts Involved in Planarian Regeneration and Analysis of Its Regeneration Patterns by PacBio Long-Read Sequencing.Front Genet, 2020, 11: 580.
          7. Fenxi Zhang, Zimei Dong?, Shuai Gao, Guangwen Chen?, Dezeng Liu.AT1R-Mediated  Apoptosis of Bone Marrow Mesenchymal Stem Cells Is Associated with mtROS  Production and mtDNA Reduction.Oxidative Medicine and Cellular Longevity,2019,4608165:1-9.
          8. Baijie Jin, Jing Ren, Jinzi Chen, Zimei Dong*, Guangwen Chen*, Dezeng Liu. Autophagy?related DjAtg1?1 plays critical role in planarian regeneration by regulating proliferation and cell death. Cell and Tissue Research, 2022, doi.org/10.1007/s00441-022-03591-3.
          9. Jing  Kang, Zimei Dong?, Hao Qin, Jing  Wang, Guangwen Chen?, Dezeng Liu.The regulation of rapamycin in planarian Dugesia japonica Ichikawa & Kawakatsu, 1964 regeneration according to TOR signaling pathway. Ecotoxicology and Environmental Safety, 2019,185:1-8.
          10. Zimei Dong, Fangfang Cheng, Yibo Yang, Fenxi Zhang, Guangwen Chen?, Dezeng Liu.Expression and functional analysis of flotillins in Dugesia japonica.Experimental Cell Research,2019,374:76-84.
          11. Qinghua Wang, Yingyu Liu, BaijieJin, Zimei Dong?, Guangwen Chen?, Dezeng Liu. Djmek is involved in planarian regeneration by regulation of cell proliferation and apoptosis.Biochem Biophys Res Commun, 2020, 532:355-361.
          12. Qinghua Wang, Lijuan Xie, Yixuan Wang, Baijie Jin , Jing Ren , Zimei Dong *,Guangwen Chen*, Dezeng Liu. Djhsp70s, especially Djhsp70c, play a key role in planarian regeneration and tissue homeostasis by regulating cell proliferation and apoptosis. Gene, 2022 820 : 146215.
          13. Yingyu Liu, JinziChen, ZimeiDong ?, Guangwen Chen ?, Dezeng Liu. Antioxidant responses and lipid peroxidation can be used as sensitive indicators for the heavymetals risk assessment of the Wei River: a casestudy of planarian Dugesia japonica. Biomarkers, 2021:26: 55-64.
          14. Jing Kang, Zimei Dong?, Jing Wang, Guangwen Chen ?, Dezeng Liu. Autophagy-related djatg8 is required for remodeling in planarian Dugesia japonica. Biology Open,2019, 045013:8-12.
          15. Zimei Dong, Gengbo Chu, Yingxu Sima, Guangwen Chen.Djhsp90s are crucial regulators during planarian regeneration and tissue homeostasis. Biochemical and Biophysical Research  Communications, 2018, 498:723-728.
          16. Zimei Dong, Yibo Yang, Guangwen Chen, Dezeng Liu. Identification of runt family genes involved in planarian regeneration and tissue homeostasis. Gene Expression Patterns,2018,29:24-31.
          17. Zimei Dong, Changying Shi, Gengbo Chu, Yanping Dong, Guangwen Chen, Dezeng Liu. Morphological changes of gonad and gene expression patterns during desexualization in Dugesia japonica (Platyhelminthes: Dugesiidae). Zoologia (Curitiba), 2018, 35:1-7.
          18. Zimei Dong, Tong Yang, Yibo Yang, He Dou, Guangwen Chen. DjhnRNPA2/B1-like gene is required for planarian regeneration and tissue homeostasis.Gene,2017,633:9-16.
          19. Zimei Dong, Yanqing Yuwen, Yingxu Sima, Yanping Dong, Huina Zhang, Guangwen Chen, Dezeng Liu. Photokinesis and Djopsin gene expression analysis during the regeneration of planarian eyes. Integrative Zoology, 2017:12:157-164.
          20. Zimei Dong, Guangwen Chen, Hecai Zhang, Dezeng Liu.A new species of Polycelis (Platyhelminthes, Tricladida, Planariidae) from China. Acta Zoologica.2017, 63(3): 263-276.
          21. Zimei Dong, Fangfang Cheng, Yanqing Yuwen, Jing Chen, Xiaoyan Li, He Dou, Haixia Zhang, Guangwen Chen, Dezeng Liu. Identification and expression analysis of a Spsb gene in planarian Dugesia japonica. Gene,2015,564:168-175.
          22. Zimei Dong, Changying Shi, Haixia Zhang, He Dou, Fangfang Cheng, Guangwen Chen, Dezeng Liu. The characteristics of sox gene in Dugesia japonica. Gene, 2014,544:177-183.
          23. Zimei Dong, Yanqing Yuwen, Qinghua Wang, Guangwen Chen, Dezeng Liu. Eight genes expression patterns during visual system regeneration in Dugesia japonica. Gene Expression Patterns,  2012,12:1-6.
          專著教材： 
          參編《動物學(xué)實驗技術(shù)》,北京,科學(xué)出版社，2008年2月。
          獎勵：
          1. 董自梅（4/6），基礎(chǔ)教育生物學(xué)拔尖人才培養(yǎng)模式研究與實踐。國家教學(xué)成果二等獎，2018。
          2．董自梅（1/6）,人體寄生蟲學(xué)教學(xué)內(nèi)容、教學(xué)方法和教學(xué)手段的改革與實踐。河南省高等教育教學(xué)成果一等獎，2016。