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          教授

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          李莉

          發(fā)布時間:2024-03-19






          姓    名:李莉

          職    稱:教授(碩士生導(dǎo)師)

          辦公電話:

          電子郵箱:lizzie406@163.com








          個人簡介:

             莉,教授,承擔(dān)《免疫學(xué)》、《人體組織解剖學(xué)》的理論課和實驗課教學(xué),曾獲河南省教育系統(tǒng)教學(xué)技能競賽一等獎、“河南省教學(xué)標(biāo)兵”、省級教學(xué)成果二等獎,博士國家獎學(xué)金。

          工作經(jīng)歷:

          2003至今,河南師范大學(xué)生命科學(xué)學(xué)院

          2016-2017,加拿大渥太華大學(xué)訪問學(xué)者

          研究領(lǐng)域:

          魚鰭再生的分子生物學(xué)。主要包括:

          (1)通過組學(xué)分析發(fā)現(xiàn)與魚鰭再生相關(guān)的基因/表達特征;

          (2)研究某一(家族)基因?qū)︳~鰭再生過程中某一階段或通路的調(diào)控機制;

          (3)以魚鰭的再生和發(fā)育模式為參考,探尋肢體再生能力在脊椎動物進化中丟失的原因。

          主要學(xué)術(shù)及社會兼職:

          中國遺傳學(xué)會會員

          中國動物學(xué)會會員

          主持或參加科研項目情況:

          近年主持的項目:

           1.泥鰍魚鰭再生過程中actinodin基因的功能解析,國家自然科學(xué)基金U1404330

           2.mmp13基因?qū)︳~鰭再生過程鰭條重建的分子調(diào)控,河南省高等學(xué)校青年骨干教師培養(yǎng)計劃2018GGJS042

           3.斑馬魚魚鰭再生過程mmp13基因的功能解析及活性增強子鑒別,河南省自然科學(xué)基金面上項目202300410243

          學(xué)術(shù)成果:

          代表性論文:

          1. Xinya Liu; Chaonan Liang;Jiaiq Fan; Li Li (corresponding author). Polyvinyl chloride microplastics induce changes in gene expression and organ histology along the HPG axis in Cyprinus carpio var.larvae. Aquatic Toxicology 258 (2023)106483(二區(qū))

          2. Xinya Liu; Chaonan Liang;Miao Zhou; Zhongjie Chang; Li Li (corresponding author). Exposure of Cyprinus carpio var. larvae to PVC microplastics reveals significant immunological alterations and irreversible histologicalorgan damage. Ecotoxicology and Environmental Safety 249 (2023) 114377(二區(qū))

          3. Xiaohua Xia, Menghan Sun, Miao Zhou, Li Li (corresponding author). Polyvinyl chloride microplastics induce growth inhibition and oxidative stress in Cyprinus carpio var.larvae. Science of The Total Environment,2020:136479(一區(qū))

          4. Li Li, Jing Zhang,Marie-Andrée Akimenko.Inhibition ofmmp13a during zebrafish fin regeneration disrupts fin growth, osteoblasts differentiation, and Laminin organization. Developmental Dynamics,2020,249:187–198  

          5. Li Li, Qian Xiao,Linlin Wang, Zhongjie Chang. Expression analysis of And4 during fin regeneration in Misgurnus anguillicaudatus provides insights into its function. Fish Physiology and Biochemistry,2019, 45:935-942

          6. Li Li, Linlin Wang,Jingya He, Zhongjie Chang. Expression of Hsp70 reveals significant differences between fin regeneration and inflammation in Paramisgurnus dabryanus. Fish and Shellfish Immunology,2017, 64:352-356(一區(qū))

          7. Li Li,Zhai Shengna,Wang Lele,Si Songbo,Wu Hailan,Chang Zhongjie. Hsp60 in caudalfin regeneration from Paramisgurnus dabryanus : Molecular cloning and expression characterization. Fish and Shellfish Immunology,2014,36(2):401-408(一區(qū))

          8. Li Li, Jingya He, Linlin Wang, Weihua Chen, Zhongjie Chang. Gene expression profiles of fin regeneration in loach (Paramisgurnus dabryanu). Gene Expression Patterns,2017, 25:124-130

          9. Li Li,Nan Ping,Zhai Shengna,Wang Lele,Si Songbo,Chang Zhongjie. Molecular cloning,characterization, and expression of hsp60 in caudal fin regeneration of Misgurnus anguillicaudatus. Molecular and Cellular Biochemistry,2014,387(1):143-150(二區(qū))