常緒路 博士/副教授
常緒路，博士生導師，院工會副主席、黨支部書記、教學秘書。從事水產微生物資源與應用研究工作，主持國家自然科學基金、河南省科技攻關、河南省高等重點科研項目等10余項。在國內外學術期刊《Aquaculture》、《Fish & Shellfish Immunology》、《Aquaculture Reports》、《Science of The Total Environment》、《Environmental Pollution》、《Environmental Research》、《Ecotoxicology and Environmental Safety》、《水產學報》等發(fā)表研究論文70余篇。主講課程《微生物學》入選河南省本科一流課程、河南省第二批課程思政樣板課程和河南省研究性教學示范課程，發(fā)表教改論文5篇，參編教材1部。
▊通訊地址
地址：河南省新鄉(xiāng)市建設路河南師范大學東區(qū)實訓樓211
郵編：453007
E-mail: changxulu@whu.edu.cn
電話：0373-3326639
▊教育背景
博士(2011/09-2016/06): 武漢大學，生命科學學院，微生物學專業(yè)
學士(2007/09-2011/06): 河南師范大學，生命科學學院，生物科學專業(yè)
▊工作經歷
2022.02-至今，河南師范大學水產學院，副教授
2016.07-2022.01，河南師范大學水產學院，講師
▊學術兼職
1.ATT亞洲區(qū)顧問
▊承擔課程
1.微生物學、微生物實驗、生物統(tǒng)計與試驗設計 (本科)
2.生物統(tǒng)計學 (研究生)
▊研究方向
1. 水產微生物資源與應用
2. 水生動物腸道微生物與環(huán)境互作
▊科教項目
1．表面蛋白BslA介導的魚源貝萊斯芽孢桿菌腸道定植規(guī)律與機制研究, 國家自然科學基金-面上項目，2024-2027，立項在研，主持
2. 凝結芽孢桿菌緩解鎘暴露導致的鯉魚腸道屏障損傷的作用及機制，國家自然科學基金-青年項目，2020-2022，結項，主持。
3．貝萊斯芽孢桿菌抗菌肽Surfactin 在大口黑鱸疾病防控中的應用，河南省重點科技攻關項目，2023-2024，立項在研，主持。
4．貝萊斯芽孢桿菌聯(lián)合葡萄糖酸鈉替代抗生素在黃河鯉健康養(yǎng)殖中的應用，新鄉(xiāng)市科技攻關，2022-2023，立項在研，主持。
5．凝結芽孢桿菌緩解鎘暴露導致鯉魚毒性損傷的作用與機制，河南省重點科技攻關項目，2020-2021，結項，主持。
6．高效低溫聚磷工程菌的構建及其在富營養(yǎng)化水體除磷中的應用，河南省重點科技攻關項目, 2019-2020，結項，主持。
7．擲孢酵母（Bullera.sp）在鯉魚養(yǎng)殖中益生作用研究，河南省高等學校重點科研項目，2019-2020，結項，主持。
8．一株分離自北極的耐低溫聚磷菌在水產養(yǎng)殖廢水除磷中的應用，河南省高等學校重點科研項目，2018-2019，結項，主持。
▊研究成果
1. Yun, Lili； Kang, Meiru; Shen, Yihao; Feng, Junchang; Yang, Guokun; Zhang, Jianxin; Meng, Xiaolin*; Chang Xulu*. Dietary Bacillus velezensis R-71003 and sodium gluconate improve antioxidant capacity, immune response and resistance against Aeromonas hydrophila in common carp. Fish & Shellfish Immunology,2023,139:108921.
2. Chang Xulu*; Kang Meiru; Yun LiLi; Shen Yihao; Feng Junchang; Yang Guokun; Zhang Jianxin; Meng Xiaolin*. Sodium gluconate increases Bacillus velezensis R-71003 growth to improve the health of the intestinal tract and growth performance in the common carp (Cyprinus carpio L.). Aquaculture, 2023, 563(01)：738980.
3. Chang Xulu; Shen Yihao; Yun Lili; Wang Xianfeng; Feng Junchang; Yang Guokun; Meng Xiaolin; Zhang Jianxin; Su Xi*; The antipsychotic drug olanzapine altered lipid metabolism in the common carp (Cyprinus carpio L.): Insight from the gut microbiota-SCFAs-liver axis, Science of The Total Environment, 2023,856(01)：159054.
4. Zhang, Jianxin; Huang, Mengyuan; Feng, Junchang; Chen, Yongyan; Li, Meng; Meng, Xiaolin; Chang Xulu*. Effect of Beneficial Colonization of Bacillus coagulans NRS 609 on Growth Performance, Intestinal Health, Antioxidant Capacity, and Immune Response of Common Carp (Cyprinus carpio L.). Aquaculture Nutrition,2023:1451394.
5. Kang Meiru; Su Xi; Yun Lili; Shen Yihao; Feng Junchang; Yang Guokun; Meng Xiaolin; Zhang Jianxin; Chang Xulu*. Evaluation of probiotic characteristics and whole genome analysis of Bacillus velezensis R-71003 isolated from the intestine of common carp (Cyprinus carpio L.) for its use as a probiotic in aquaculture. Aquaculture Reports, 2022, 25：101254.
6. Chang Xulu*, Chen Yongyan, Feng Junchang, Huang Mengyuan, Zhang Jianxin, Amelioration of Cd-induced bioaccumulation, oxidative stress and immune damage by probiotic Bacillus coagulans in common carp (Cyprinus carpio L.), Aquaculture Reports, 2021, 20: 0-100678
7. Chang Xulu, Kang Meiru, Shen Yihao, Yun Lili, Yang Guokun, Zhu Lei, Meng Xiaolin, Zhang Jianxin, Su Xi*, Bacillus coagulans SCC-19 maintains intestinal health in cadmium-exposed common carp (Cyprinus carpio L.) by strengthening the gut barriers, relieving oxidative stress and modulating the intestinal microflora, Ecotoxicology and Environmental Safety, 2021, 228: 0-112977
8. Zhang Jianxin, Huang Mengyuan, Feng Junchang, Chen Yongyan, Li Meng, Chang Xulu*, Effects of dietary Bacillus licheniformis on growth performance, intestinal morphology, intestinal microbiome, and disease resistance in common carp (Cyprinus carpio L.) Aquaculture International, 2021, 29(3): 1343-1358
9. Su Xi, Li Wenqiang, Li Zhen, Liu Kang, Song Meng, Shao Minglong, Lv Luxian, Chang Xulu*, Chronic developmental exposure to low-dose ([C8mim][PF6]) induces neurotoxicity and behavioural abnormalities in rats. Ecotoxicology and Environmental Safety, 2021, 225: 0-112806
10．Chang Xulu, Wang Xianfeng, Feng Junchang, Su Xi, Liang Junping, Li Hui, Zhang Jianxin*, Impact of chronic exposure to trichlorfon on intestinal barrier, oxidative stress, inflammatory response and intestinal microbiome in common carp (Cyprinus carpio L.), Environmental Pollution, 2020, 259:113846
11．Chang Xulu, Liu Ping, Feng Junchang, Su Xi, Huang Mengyuan, Chen Yongyan, Zhang Jianxin*, Li Baohua*, Impact of chronic exposure to the ionic liquid ([C8mim][PF6]) on intestinal physical barrier, immunological barrier and gut microbiota in common carp (Cyprinus carpio L.), Environmental Research, 2020, 189:109919
12．Chang Xulu, Li Hui, Feng Junchang, Chen Yongyan, Nie Guoxing, Zhang Jianxin?, Effects of cadmium exposure on the composition and diversity of the intestinal microbial community of common carp (Cyprinus carpio L.), Ecotoxicology and Environmental Safety, 2019, 171: 92-98
13．Chang Xulu, Feng Junchang, Guo Xiangrui, Huang Mengyuan, Nie Guoxing, Zhang Jianxin*, Dietary supplementation with Rehmannia glutinosa affects the composition of intestinal microorganisms in common carp, Journal of Basic Microbiology, 2018, 58(12):1023-1032
▊獲獎榮譽
1．首屆高校大學生水產類創(chuàng)新實踐能力大賽全國總決賽優(yōu)秀指導教師
2. 2023年度河南師范大學優(yōu)秀黨務工作者
3. 2021年度河南師范大學急難險重先進個人
4．2020年度河南師范大學優(yōu)秀共產黨員
5．2018年度河南師范大學文明教師
