謝明勝

有機(jī)化學(xué)，教授，博導(dǎo)，俊甫書(shū)院副院長(zhǎng)

國(guó)家優(yōu)秀青年基金獲得者（2024年）

全國(guó)高校青年教師教學(xué)競(jìng)賽理科組二等獎(jiǎng)（第六屆，2023年）

河南省政府特殊津貼專家（第六批，2024年）

平原學(xué)者（拔尖人才）（2022年入選）

中原英才計(jì)劃（育才系列）——中原青年拔尖人才（2021年入選）

河南省優(yōu)秀青年基金獲得者（2020年入選）

河南省優(yōu)秀教師（2023）

河南省優(yōu)秀碩士學(xué)位論文指導(dǎo)教師（2020年入選）

河南省教育廳學(xué)術(shù)技術(shù)帶頭人(2019年入選)

河南省高?？萍紕?chuàng)新團(tuán)隊(duì)支持計(jì)劃獲得者（2022）

河南省高?？萍紕?chuàng)新人才（2019年入選）

河南省教學(xué)標(biāo)兵（2021）

新鄉(xiāng)市市長(zhǎng)教育質(zhì)量獎(jiǎng)——名教師質(zhì)量獎(jiǎng)獲得者（2021年入選）

新鄉(xiāng)市首屆五四青年獎(jiǎng)?wù)拢?022）

河南師范大學(xué)第六屆青年教師課堂教學(xué)十佳教師（2021年入選）

Email:xiemingsheng@htu.edu.cn

教育與研究經(jīng)歷：

2004年9月-2008年6月  四川大學(xué)     化學(xué)學(xué)院 理學(xué) 學(xué)士

2008年9月-2013年6月  四川大學(xué)     化學(xué)學(xué)院 理學(xué) 博士

2013年7月-至今      河南師范大學(xué)   化學(xué)化工學(xué)院 歷任講師、副教授、教授

主講課程：

本科生：《有機(jī)化學(xué)》理論課/主干課

研究生：《有機(jī)波譜分析》必修課/專業(yè)主干課

研究領(lǐng)域與興趣：

1、手性親核催化劑的設(shè)計(jì)及應(yīng)用

2、手性吡啶配體的設(shè)計(jì)及應(yīng)用

3、手性核苷的不對(duì)稱合成

主持的科研項(xiàng)目：

國(guó)家優(yōu)秀青年科學(xué)基金、國(guó)家自然科學(xué)基金面上項(xiàng)目（已結(jié)項(xiàng)）、青年項(xiàng)目（已結(jié)項(xiàng)）等

獲獎(jiǎng)：

1、在中華全國(guó)總工會(huì)、教育部聯(lián)合主辦的第六屆全國(guó)高校青年教師教學(xué)競(jìng)賽中榮獲理科組二等獎(jiǎng)（2023.04）

2、“催化不對(duì)稱[8+2]環(huán)加成反應(yīng)構(gòu)建環(huán)庚三烯并吡咯烷-3,3'-吲哚酮,《化學(xué)學(xué)報(bào)》,2014年7月，謝明勝，武曉霞，王剛，林麗麗，馮小明*” 獲得“第三屆中國(guó)科協(xié)優(yōu)秀科技論文”（2018年10月）

3、第二屆“盧錦梭師德楷模獎(jiǎng)教金”

4、河南省優(yōu)秀教師（2023年8月）

5、河南省教育系統(tǒng)教學(xué)技能競(jìng)賽一等獎(jiǎng)（高校理科組第二名）（2021年10月）

6、河南省教學(xué)標(biāo)兵（2021年10月）

7、新鄉(xiāng)市市長(zhǎng)教育質(zhì)量獎(jiǎng)——名教師質(zhì)量獎(jiǎng)（2021年9月）

8、河南師范大學(xué)第六屆青年教師課堂教學(xué)比賽一等獎(jiǎng)（理科組第一名）（2021年7月）

9、河南師范大學(xué)第六屆青年教師課堂教學(xué)十佳教師（2021年7月）

10、2018-2020學(xué)年度河南師范大學(xué)“優(yōu)秀教師”榮譽(yù)稱號(hào)

11、2022年度河南師范大學(xué)“五四青年獎(jiǎng)?wù)隆?/span>

12、2016年度河南師范大學(xué)“新聞宣傳先進(jìn)個(gè)人”榮譽(yù)稱號(hào)

代表性論文：

[1] Tao Wei, Han-Le Wang, Yin Tian*, Ming-Sheng Xie*, Hai-Ming Guo*, Enantioselective construction of stereogenic-at-sulfur(IV) centers via catalytic acyl transfer sulfinylation, Nature Chemistry, 2024, 16, 1301-1311.

[2] Hai-Xia Wang, Chun Yang, Bai-Yu Xue, Ming-Sheng Xie*, Yin Tian*, Cheng Peng, and Hai-Ming Guo* Design of C1-symmetric tridentate ligands for enantioselective dearomative [3?+?2] annulation of indoles with aminocyclopropanes, Nat. Commun. 2023, 14, 2270.

[3] Ming-Sheng Xie*, Bin Huang, Ning Li, Yin Tian*, Xiao-Xia Wu, Yun Deng, Gui-Rong Qu, and Hai-Ming Guo* Rational Design of 2-Substituted DMAP-N-oxides as Acyl Transfer Catalysts: Dynamic Kinetic Resolution of Azlactones.J. Am. Chem. Soc. 2020, 142(45), 19226-19238.(Highlight by Synfacts和X-MOL)

[4] Ming-Sheng Xie,* Ye-Fei Zhang, Meng Shan, Xiao-Xia Wu, Gui-Rong Qu, and Hai-Ming Guo*, Chiral DMAP-N-Oxides as Acyl Transfer Catalysts: Design, Synthesis, and Application in Asymmetric Steglich Rearrangement, Angew. Chem. Int. Ed. 2019, 58(9), 2839-2843 (Highlight by 《有機(jī)化學(xué)》和X-MOL).

[5] Ming-Sheng Xie*, Meng Shan, Ning Li, Yang-Guang Chen, Xiao-Bing Wang, Xuan Cheng, Yin Tian*, Xiao-Xia Wu, Yun Deng, Gui-Rong Qu, and Hai-Ming Guo* Chiral 4-Aryl-Pyridine-N-oxide Nucleophilic Catalysts: Design, Synthesis, and Application in Acylative Dynamic Kinetic Resolution. ACS Catalysis, 2022, 12, 877-891.

[6] Ming-Sheng Xie*, Ning Li, Yin Tian*, Xiao-Xia Wu, Yun Deng, Gui-Rong Qu, and Hai-Ming Guo* Dynamic Kinetic Resolution of Carboxylic Esters Catalyzed by Chiral PPY-N-oxides: Synthesis of Nonsteroidal Anti-Inflammatory Drugs and Mechanistic Insights, ACS Catalysis, 2021, 11, 8183-8196. 

[7] Heng-Bin Yu, Yang-Guang Chen, Yin Tian*, Ming-Sheng Xie*, Hai-Ming Guo*, Nickel(II)-Catalyzed Asymmetric Inverse-Electron-Demand Diels–Alder Reaction of 2-Pyrones with Styrenes and Indenes, ACS Catalysis, 2024, 14, 11, 8930-8938.

[8] Xing-Yu Wang, Xiao-Bing Wang, Yin Tian*, Cheng Peng, Ming-Sheng Xie*, Hai-Ming Guo*, Cobalt-Catalyzed Asymmetric Dearomative [3 + 2] Annulation of Quinolines, Isoquinolines, and Pyridines, ACS Catal. 2023, 13, 17, 11528-11540.

[9] Chen-Ying Hou, Chun Yang, Yin Tian*, Ming-Sheng Xie*, Hai-Ming Guo*, Achiral Counteranion-Induced Reversal of Enantioselectivity in Ni(II)-Catalyzed Friedel–Crafts Alkylation/Annulation of 2-Naphthols, Org. Lett., 2024, 26, 30, 6390-6395.

[10] Yu-Lin Gao, Yang Yang, Chen Wu, Ming-Sheng Xie*, Hai-Ming Guo*, Chemoselectivity Switch between Enantioselective [2,3]-Wittig Rearrangement and Conia-Ene-Type Reactions of Propargyloxyoxindoles, Chem. Eur. J. 2024, 30, 56, e202402556.

[11] Ru-Lin Luo, Xiao-Bing Wang, Ming-Sheng Xie*, Hai-Ming Guo*, Catalytic asymmetric ring-opening of aminocyclopropanes with oxygen nucleophiles: access to chiral γ-amino acid derivatives, Org. Chem. Front., 2024, 11, 1817-1823.

[12] Jun-Hao Zhang, Wei-Jing Yang, Ning Li, Yin Tian*, Ming-Sheng Xie*, Hai-Ming Guo*, Reversal of enantioselectivity in cobalt(II)-catalyzed asymmetric Michael–alkylation reactions: synthesis of spiro-cyclopropane-oxindoles, Org. Chem. Front., 2024,11, 4007-4013.

[13] Han-Le Wang, Tao Wei, Ru-Yun Bi, Ming-Sheng Xie*, Hai-Ming Guo*, Imidazolidine-Pyrroloimidazolone Pyridine-Ni(acac)2 Complex Catalyzed Asymmetric Darzens Reaction of Isatins with Phenacyl Chlorides: A Chiral Amplification Effect, Adv. Synth. Catal., 2024, 366, 14, 3188-3193.

[14]Ya-Ping Wang, Xing-Ping Zhang, Ming-Sheng Xie*, Hai-Ming Guo*, Cobalt(II)-Catalyzed Enantioselective Propargyl Claisen Rearrangement: Access to Allenyl-Substituted Quaternary β-Ketoesters, Org. Lett., 2023, 25, 39, 7105-7109.

[15] Bai-Yu Xue, Chen-Ying Hou, Xiao-Bing Wang, Ming-Sheng Xie*, Hai-Ming Guo*, Asymmetric synthesis of 7-membered-ring-bridged 3,4-fused tricyclic indoles?via?Friedel–Crafts alkylation/annulation, Org. Chem. Front., 2023, 10, 1910-1914.

[16] Xiao-Bing Wang, Yin Tian, Li Zhou, Ming-Sheng Xie*, Gui-Rong Qu, and Hai-Ming Guo, Rational Design of Chiral Tridentate Ligands: Bifunctional Cobalt(II) Complex/Hydrogen Bond for Enantioselective Michael Reactions, Org. Lett. 2022, 24, 21, 3861–3866.

[17] Yang-Guang Chen, Heng-Bin Yu, Yin Tian*, Cheng Peng, Ming-Sheng Xie*, Hai-Ming Guo*, ArPNO-Catalyzed Acylative Dynamic Kinetic Resolution of 3-Hydroxyphthalides: Access to Enantioenriched Phthalidyl Esters, Org. Lett. 2023, 25, 5585-5590.

[18] Yang-Guang Chen, Ying Hu, Jia-Yi Liu, Ming-Sheng Xie*, Hai-Ming Guo*, Pyridine-N-oxide catalyzed acylative desymmetrization of bisphenols: access to P-stereogenic phosphinates with low catalyst loadings, Org. Chem. Front., 2023, 10, 6140-6145. 

[19] Sai-Ya Lian, Ning Li, Yin Tian*, Cheng Peng, Ming-Sheng Xie*, Hai-Ming Guo, Reversal of Enantioselectivity for the Desymmetrization of meso-1,2-Diols Catalyzed by Pyridine-N-oxides, J. Org. Chem. 2023, 88, 13771-13781.

[20] Lei Cao, Xing-Ping Zhang, Ming-Sheng Xie,* and Hai-Ming Guo Cu-Catalyzed N-Arylation of Prolinamides: Access to Enantioenriched DMAP Analogues and Its Application in Black Rearrangement, J. Org. Chem.2023, 88(1), 341-346.

[21] Min Yang, Yu-Lin Gao, Ming-Sheng Xie,* and Hai-Ming Guo* ArPNO-catalyzed acylative kinetic resolution of tertiary alcohols: access to 3-hydroxy-3-substituted oxindoles, Org. Biomol. Chem., 2022, 20(32), 6351-6355.

[22] Meng Shan, Tao Liang, Ye-Fei Zhang, Ming-Sheng Xie,* Gui-Rong Qu, and Hai-Ming Guo* Enantioselective rearrangement of indolyl carbonates catalyzed by chiral DMAP-N-oxides, Org. Chem. Front. 2019, 6(23), 3874-3878.

[23]Huifang Zhang, Mingsheng Xie,* Guirong Qu, and Junbiao Chang* Dynamic Kinetic Resolution of α-Purine Substituted Alkanoic Acids: Access to Chiral Acyclic Purine Nucleosides, Org. Lett. 2019, 21(1), 120-123.

[24] Ming-Sheng Xie,* Yang-Guang Chen, Xiao-Xia Wu, Gui-Rong Qu, and Hai-Ming Guo* Asymmetric Synthesis of Chiral Acyclic Purine Nucleosides Containing a Hemiaminal Ester Moiety via Three-Component Dynamic Kinetic Resolution, Org. Lett. 2018, 20(4), 1212-1215.

[25] Ming-Sheng Xie, Guo-Feng Zhao, Tao Qin, Yong-Bo Suo, Gui-Rong Qu, and Hai-Ming Guo*, Thiourea participation in [3+2] cycloaddition with donor–acceptor cyclopropanes: a domino process to 2-amino-dihydrothiophenes, Chem. Commun. 2019, 55(11), 1580-1583.

[26] Tao Qin, Jian-Ping Li, Ming-Sheng Xie,* Gui-Rong Qu, and Hai-Ming Guo*, Synthesis of Chiral Acyclic Nucleosides by Sharpless Asymmetric Dihydroxylation: Access to Cidofovir and Buciclovir, J. Org. Chem.2018, 83(24), 15512-15523.

[27] Ming-Sheng Xie,* Xuan Cheng (成軒，本科生), Yang-Guang Chen, Xiao-Xia Wu, Gui-Rong Qu, and Hai-Ming Guo*, Efficient synthesis of tetrazole hemiaminal silyl ethers via three-component hemiaminal silylation, Org. Biomol. Chem. 2018, 16(38), 6890-6894.

[28] Mingsheng Xie, Xiaohua Liu, Xiaoxia Wu, Yunfei Cai, Lili Lin and Xiaoming Feng*, Catalytic Asymmetric [8+2] Cycloaddition: Synthesis of Cycloheptatriene-Fused Pyrrole Derivatives，Angew. Chem. Int. Ed. (2013), 52, 5604-5607.  

[29]  Mingsheng Xie, Xiaohong Chen, Yin Zhu, Bo Gao, Lili Lin, Xiaohua Liu and Xiaoming Feng*，Asymmetric Three-Component Inverse Electron-Demand Aza-Diels–Alder Reaction: Efficient Synthesis of Ring-Fused Tetrahydroquinolines，Angew. Chem. Int. Ed. (2010), 49, 3799-3801. 

[30] 謝明勝, 武曉霞, 王剛, 林麗麗, 馮小明*, 催化不對(duì)稱[8+2]環(huán)加成反應(yīng)構(gòu)建環(huán)庚三烯并吡咯烷-3,3’-吲哚酮，化學(xué)學(xué)報(bào)，2014，72, 856-861.

[31] Mingsheng Xie, Xiaohua Liu, Yin Zhu, Xiaohu Zhao, Yong Xia, Lili Lin and Xiaoming Feng*, Asymmetric Synthesis of Tetrahydroquinolines with Quaternary Stereocenters via Povarov Reaction, Chemistry–A European Journal (2011), 17, 13800-13805.