個人簡介：

蘇莉，博士，副教授，碩士生導(dǎo)師

電話：15837369659 

 E-mail：suli@htu.edu.cn

教育經(jīng)歷：
2004.9-2008.6  信陽師范學(xué)院  化學(xué)化工學(xué)院  理學(xué)學(xué)士

2008.9-2013.6  蘭州大學(xué)          化學(xué)化工學(xué)院  理學(xué)博士

工作經(jīng)歷：

2013.7-至今     河南師范大學(xué)  化學(xué)化工學(xué)院    講師、副教授

研究領(lǐng)域與興趣：

1、納米酶材料的設(shè)計合成

2、生化分析、生物傳感與生物成像

3、活性氧調(diào)控與疾病治療

近年來主持的主要科研項目:
1、國家自然科學(xué)基金: 酞菁類MOFs材料模擬酶的設(shè)計合成及其在可視化檢測中的應(yīng)用研究, 項目編號: 21405034, 2015.1-2017.12

2、河南省科技攻關(guān)項目: 新型金屬有機骨架納米酶傳感體系的構(gòu)建及其在有機磷農(nóng)藥殘留檢測中的應(yīng)用, 項目編號: 192102210041, 2019.1-2020.12

3、河南師范大學(xué)國家級科研項目培育基金: 多色熒光碳基納米酶生物傳感器的構(gòu)建及活細胞內(nèi)過氧化氫檢測與成像分析, 項目編號: 2019PL12, 2019.1-2021.12

4、河南省高等學(xué)校重點科研項目: 磁性納米材料模擬酶的催化機理及其應(yīng)用研究, 項目編號: 14B150020, 2014.1-2016.12

代表性論文：

[10] Li Su*, Sainan Qin, Zhongjian Xie, Liang Wang*, Karim Khan, Ayesha Khan Tareen, Defa Li*, Han Zhang*, Multi-enzyme activity nanozymes for biosensing and disease treatment. Coordination Chemistry Reviews, 2022, 473, 214784.  

[9] Li Su*, Sainan Qin, Yexi Cai, Liang Wang, Wenpei Dong, Guojiang Mao, Suling Feng, Zhongjian Xie*, Han Zhang*, Co, N-doped carbon dot nanozymes with acid pH-independence and substrate selectivity for biosensing and bioimaging. Sensors and Actuators B: Chemical, 2022, 353: 131150.  

[8] Li Su*,  Yexi Cai, Liang Wang,  Wenpei Dong,  Guojiang Mao, Ye Li, Mingsheng Zhao, Yanhua Ma, Hua Zhang*.  Hemin@carbon dot hybrid nanozymes with peroxidase mimicking properties for dual (colorimetric and fluorometric) sensing of hydrogen peroxide, glucose and xanthine. Microchimica Acta, 2020, 187, 132.

[7] Li Su*, Xinai Yu, YuqiMiao, Guojiang Mao, Wenpei Dong, Suling Feng, Siman Liu, Like Yang, Kaige Zhang, Hua Zhang*. Alkaline-promoted regulation of the peroxidase-like activity of Ni/Co LDHs and development bioassays. Talanta, 2019, 197, 181-188.

[6] Li Su*, Xinai Yu, Yexi Cai, Puhua Kang, Wenjie Qin, Wenpei Dong, Guojiang Mao, Suling Feng*. Evaluation of fluorogenic substrates for Ni/Co LDHs peroxidase mimic and application for determination of inhibitory effects of antioxidant. Analytica Chimica Acta, 2017, 987, 98-104.

[5] Li Su*, Wenpei Dong, Chengke Wu, Yijun Gong, Yan Zhang, Ling Li, Guojiang Mao, Suling Feng*. The peroxidase and oxidase-like activity of NiCo₂O₄ mesoporous spheres: Mechanistic understanding and colorimetric biosensing. Analytica Chimica Acta, 2017, 951,124-132.

[4] Li Su*, Xinai Yu, Wenjie Qin, Wenpei Dong, Chengke Wu, Yan Zhang, Guojiang Mao and Suling Feng*. One-step analysis of glucose and acetylcholine in water based on the intrinsic peroxidase-like activity of Ni/Co LDHs microspheres. Journal of Materials Chemistry B, 2017, 5, 116-122.

[3] Li Su, Wenjie Qin, Huige Zhang, Zia Ur Rahman, Cuiling Ren, Sudai Ma, Xingguo Chen*. The peroxidase/catalase-like activities of MFe₂O₄ (M=Mg, Ni, Cu) MNPs and their application in colorimetric biosensing of glucose. Biosensors and Bioelectronics,2015, 63, 384-391. （截止2020年7月被引109次）

[2] Li Su, Jie Feng, Ximin Zhou, Cuiling Ren, Honghong Li, Xingguo Chen*. Colorimetric detection of urine glucose based ZnFe₂O₄ magnetic nanoparticles. Analytical Chemistry, 2012, 84, 5753-5758.（截止2020年7月被引309次）

[1] Li Su, Lina Li, Yanwei Li, Xiaoyun Zhang*, Xiaoyan Huang, Honglin Zhai. Simple and accurate approaches to predict the activity of benzothiadiazine derivatives as HCV inhibitors. Medicinal Chemistry Research, 2012, 21:2079–2096

合作論文:

[1] Mao G-J, Gao G-Q, Liang Z-Z, Wang Y-Y, Su L, Wang Z-X, Zhang H, Ma Q-J, Zhang G. A mitochondria-targetable two-photon fluorescent probe with a far-red to near-infrared emission for sensing hypochlorite in biosystems. Analytica Chimica Acta, 2019, 1081: 184-192.

[2] Mao G-J, Liang Z-Z, Bi J, Zhang H, Meng H-M, Su L, Gong Y-J, Feng S, Zhang G. A near-infrared fluorescent probe based on photostable Si-rhodamine for imaging hypochlorous acid during lysosome-involved inflammatory response. Analytica Chimica Acta, 2019, 1048: 143-153.

[3] Mao G-J, Liang Z-Z, Gao G-Q, Wang Y-Y, Guo X-Y, Su L, Zhang H, Ma Q-J, Zhang G. A photostable Si-rhodamine-based near-infrared fluorescent probe for monitoring lysosomal pH during heat stroke. Analytica Chimica Acta, 2019, 1092: 117-125.

[4] Gong Y-J, Zhang X-B, Mao G-J, Su L, Meng H-M, Tan W, Feng S, Zhang G. A unique approach toward near-infrared fluorescent probes for bioimaging with remarkably enhanced contrast. Chem Sci, 2016, 7: 2275-2285.

[5] Duan J, Yu J, Feng S, Su L. A rapid microwave synthesis of nitrogen-sulfur co-doped carbon nanodots as highly sensitive and selective fluorescence probes for ascorbic acid. Talanta, 2016, 153: 332-339.

[6] Cui Y, Gong Y-J, Su L, Wu C-K, Pang S-B, Feng S-L. Spectroscopy studies of sandwich-type complex of silver(I) co-ordinated to nuclear fast red and adenine and its analytical applications. Chemical Papers, 2015, 69: 510-517.

[7] Wu C, An X, Gao S, Su L. Self-assembly of cuprous oxide nanoparticles supported on reduced graphene oxide and their enhanced performance for catalytic reduction of nitrophenols. Rsc Advances, 2015, 5: 71259-71267.

[8] Qin W, Su L, Yang C, Ma Y, Zhang H, Chen X. Colorimetric Detection of Sulfite in Foods by a TMB-O₂-Co₃O₄ Nanoparticles Detection System. Journal of Agricultural and Food Chemistry, 2014, 62: 5827-5834.

[9] Feng J, Su L, Ma Y, Ren C, Guo Q, Chen X. CuFe₂O₄ magnetic nanoparticles: A simple and efficient catalyst for the reduction of nitrophenol. Chemical Engineering Journal, 2013, 221: 16-24.

[10] Zhou X, Lu W, Su L, Dong Y, Li Q, Chen X. The binding affinity of amino acid-protein: hydroxyproline binding site I on human serum albumin. Organic & Biomolecular Chemistry, 2012, 10: 8314-8321.

[11] Zhou X-M, Lue W-J, Su L, Shan Z-J, Chen X-G. Binding of Phthalate Plasticizers to Human Serum Albumin in Vitro: A Multispectroscopic Approach and Molecular Modeling. Journal of Agricultural and Food Chemistry, 2012, 60: 1135-1145.

[12] Ji C, Li Y, Su L, Zhang X, Chen X. Quantitative structure-retention relationships for mycotoxins and fungal metabolites in LC-MS/MS. Journal of Separation Science, 2009, 32: 3967-3979.

授權(quán)專利：

1、蘇莉，于心愛，張艷，等. 一種規(guī)?；苽涮蓟旌线^渡金屬氧化物多孔微球的方法，ZL201510819333.1

2、蘇莉，于心愛，董文佩，等. 一種規(guī)?；苽溥^渡金屬氧化物多孔微球的方法，ZL201510819790.0

3、蘇莉，蔡曄茜，毛國江，等. 基于比色熒光雙通道的納米模擬酶及其在分析檢測中應(yīng)用. ZL201711433046.2

獲得榮譽與獎勵：

1、2018年6月 指導(dǎo)學(xué)生獲得“2018年河南師范大學(xué)優(yōu)秀碩士畢業(yè)論文”。

2、2018年9月 獲“河南師范大學(xué)優(yōu)秀教師”。

3、河南省教育廳科技成果獎優(yōu)秀科技論文(Analytica Chimica Acta, 2017, 951,124-132), 一等獎, 2020.

4、河南省教育廳科技成果獎優(yōu)秀科技論文(Journal of Materials Chemistry B, 2017, 5, 116-122.), 二等獎, 2020.

5、2021年10月獲得河南省教育系統(tǒng)教學(xué)技能技能競賽三等獎。