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          王東超個人簡介

          時間:2020-07-18瀏覽:12028設(shè)置

           

          王東超,男,中共黨員,博士,教授,碩士生導(dǎo)師,河南省高??萍紕?chuàng)新團(tuán)隊帶頭人,河南省高校青年骨干教師。 

          1997-2001年,河南師范大學(xué),學(xué)士

          2005-2008年,河南師范大學(xué),碩士

          2013-2016年,河南師范大學(xué),博士

          電話:0373-3329276

          Email: wangdc@htu.edu.cn


           

           

           
           
           

          主講課程:
          有機(jī)化學(xué),有機(jī)化學(xué)實驗,不對稱催化
          研究領(lǐng)域與興趣:
          核苷類化合物的合成,不對稱去芳構(gòu)化反應(yīng),Heck串聯(lián)反應(yīng)

          主持項目:

          1. 國家自然科學(xué)基金聯(lián)合基金,U2004187,不對稱去芳構(gòu)化環(huán)加成反應(yīng)合成三環(huán)嘌呤核苷類化合物,2021/01-2023/12,在研,主持;

          2. 河南省高校科技創(chuàng)新團(tuán)隊,22IRTSTHN003,核苷類化合物的合成及生物活性,2022/01-2024/12,在研,主持

          3. 河南省自然科學(xué)基金面上項目,202300410245,嘌呤類化合物的不對稱去芳構(gòu)化環(huán)加成反應(yīng),2020/09-2022/09,結(jié)項,主持

          4. 橫向項目,5-氟尿嘧啶與尿苷二磷酸生產(chǎn)新工藝的技術(shù)開發(fā),2019/08-2023/12,在研,主持;

          5. 河南省高校青年骨干教師支持計劃,2017GGJS042,嘌呤類化合物的去芳構(gòu)化反應(yīng)研究,2018/01-2020/12,結(jié)項,主持;

          6. 省高等學(xué)校重點科研項目,18A150007,基于D-A環(huán)丙烷的不對稱[3+2]環(huán)加成反應(yīng)合成非芳香的嘌呤(核苷)類化合物,2017/01-2019/12結(jié)項,主持;

          代表性論文:

          20. Dong-Chao Wang,* Jia-Hui Liu, Yu-Qing Guan, and Hai-Ming Guo*, Dearomative [4 + 2] Annulation of Electron-Poor N-Heteroarenes with Azoalkenes for Access to Polycyclic Tetrahydro-1,2,4-triazines.  Org. Lett. 2023, 25(19), 3543?3547.

          19. Dong-Chao Wang,* Pan-Pan Wu, Pei-Yu Du, Gui-Rong Qu, and Hai-Ming Guo*, Highly Diastereoselective Synthesis of Oxindoles Containing Vicinal Quaternary and Tertiary Stereocenters by a Domino Heck/Decarboxylative Alkynylation Sequence. Org. Lett. 2022, 24(23), 4212-4217.

          18. Dong-Chao Wang,* Ting-Ting Yang, Gui-Rong Qu, and Hai-Ming Guo*, Substrate-Dependent Regioselectivity: Pd/PTC Cooperatively Catalyzed Domino Heck/Allylation of Allenamides with α-Carbon of Carbonyl Compounds.  J. Org. Chem. 2022, 87(21), 14284-14298.

          17. Meng-Cheng Zhang, Dong-Chao Wang,* Hai-Ting Wang, Gui-Rong Qu, and Hai-Ming Guo*, Highly Chemoselective Synthesis of Purino[3,2-c]oxazoles via the Asymmetric Dearomative [3+2] Cycloaddition of Purines with Donor–Acceptor Oxiranes. Org. Lett. 2022, 24(41), 7527-7532.

          16. Dong-Chao Wang,* Peng-Peng Cheng, Ting-Ting Yang, Pan-Pan Wu, Gui-Rong Qu, Hai-Ming Guo*, Asymmetric Domino Heck/Dearomatization Reaction of β-Naphthols to Construct Indole–Terpenoid Frameworks. Org. Lett. 2021, 23(20), 7865-7872. (CBG亮點介紹)

          15. Zhen Wang, Dong-Chao Wang*, Ming-Sheng Xie, Gui-Rong Qu, Hai-Ming Guo*Enantioselective Synthesis of Fused Polycyclic Tropanes via Dearomative [3 + 2] Cycloaddition Reactions of 2-NitrobenzofuransOrg. Lett. 2020, 1, 164-167. (CBG亮點介紹 )

          14. Meng-Cheng Zhang, Dong-Chao Wang, Ming-Sheng Xie, Gui-Rong Qu,Hai-Ming Guo,* Shu-Li You,* Cu-catalyzed Asymmetric Dearomative [3 + 2] Cycloaddition Reaction of Benzazoles with Aminocyclopropanes, Chem 2019, 5(1), 156-167.Highly cited paper, May/2019,WeeChem亮點介紹該工作)

          13. Dong-Chao Wang, Ming-Sheng Xie, Hai-Ming Guo*, Gui-Rong Qu, Meng-Cheng Zhang, Shu-Li You*, Enantioselective Dearomative [3+2] Cycloaddition Reactions of Benzothiazoles, Angew. Chem. Int. Ed. 2016, 55, 14111–14115. (highlighted by Synfacts)

          12. Zhen Wang, Dong-Chao Wang*, Ming-Sheng Xie, Gui-Rong Qu, Hai-Ming Guo*, Enantioselective Synthesis of Fused Polycyclic Tropanes via Dearomative [3 + 2] Cycloaddition Reactions of 2-Nitrobenzofurans, Org. Lett. 2020, 1, 164-167.

          11. Lei Liang, Hong-ying Niu, Dong-Chao Wang*, Xin-he Yang, Gui-Rong Qu, Hai-Ming Guo*, Facile Synthesis of Chiral [2,3]-Fused Hydrobenzofuran via Asymmetric Cu(I)-Catalyzed Dearomative 1,3-Dipolar Cycloaddition, Chem. Commun. 2019, 55, 553-556. Highly cited paper, July/2019

          10. Xin-He Yang, Jian-Ping Li, Dong-Chao Wang*, Ming-Sheng Xie, Gui-Rong Qu, Hai-Ming Guo*, Enantioselective Dearomative [3+2] Cycloaddition of 2-Nitrobenzofurans with Aldehyde-Derived Morita?Baylis?Hillman Carbonates, Chem. Commun. 2019, 55, 9144-9147.

          9. Er-Jun Hao, Dan-Dan Fu, Dong-Chao Wang,* Tao Zhang, Gui-Rong Qu, Gong-Xin Li, Yu Lan,* and Hai-Ming Guo*, Chemoselective Asymmetric Dearomative [3+2] Cycloaddition Reactions of Purines with Aminocyclopropanes, Org. Chem. Front. 2019, 6, 863-867.

          8. Man Zhu, Dong-Chao Wang,* Ming-Sheng Xie, Gui-Rong Qu, Hai-Ming Guo,* Enantioselective Friedel-Crafts Alkylation Reactions of β-Naphthols with D-A Aminocyclopropanes, Chem. Eur. J. 2018, 24(58), 15512-15516.

          7. Shan-Shan Zhang, Dong-Chao Wang*, Ming-Sheng Xie, Gui-Rong Qu, Hai-Ming Guo*,Highly Chemo- and Diastereoselective Dearomative [3 + 2] Cycloaddition Reactions of Benzazoles with Donor–Acceptor Oxiranes, Org. Lett. 2018, 20(24), 8026–8029.

          6. Dong-Chao Wang, Hai-Xia Wang, Er-Jun Hao, Xiao-Han Jiang, Ming-Sheng Xie, Gui-Rong Qu* and Hai-Ming Guo*, Synthesis of 3,3-Disubstituted Oxindoles Containing a 3-(4-Aminobut-2-ynyl) Unit via Domino Heck–Sonogashira Reaction in Water, Adv. Synth. Catal. 2016, 358: 494499.as a VIP paper. see Inside cover

          5. Dong-chao Wang, Ran Xia, Ming-sheng Xie, Gui-rong Qu*, Hai-ming Guo*, Synthesis of Cycloalkyl Substituted Purine Nucleosides via a Metal-Free Radical Route, Org. Biomol. Chem. 2016, 14, 4189-4193. (Invited paper )

          4. Dong-Chao Wang, Hong-Ying Niu, Ming-Sheng Xie, Gui-Rong Qu,* Hui-Xuan Wang, and Hai-Ming Guo,*Highly Regioselective Three-Component Domino Heck?Negishi Coupling Reaction for the Functionalization of Purines at C6, Org. Lett. 2014, 16, 262-265.

          3. Dong-Chao Wang, Hong-Ying Niu, Gui-Rong Qu, Lei Liang, Xue-Jiao Wei, Yi Jiang, Hai-Ming Guo, Nickel-catalyzed Negishi cross-couplings of 6-chloropurines with organozinc halides at room temperature, Organic & Biomolecular Chemistry 2011, 9, 7663-7666.

          2. Dong-Chao Wang, Hai-Ming Guo, Gui-Rong QuEfficient, Green, Solvent-Free Synthesis of 3,4-Dihydropyrimidin-2(1H)-ones via Biginelli Reaction Catalyzed by Cu(NO3)2·3H2O, Synthetic Communications 2010,  40, 1115–1122.

          1. Dongchao Wang, Hongying Niu,  Haiming Guo,  Xuejiao Wei, Ruifang Ding, Guirong Qu*,  Nickel-Catalyzed Negishi Cross-Coupling Reactions of Secondary Alkylzinc Halides with 6-Chloropurines, Chin. J. Org. Chem. 2012, 32, 1072-1076

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