?？?/title> <meta name="description" content="研究方向：有機化學、新藥研究與開發(fā)?？?，博士，教授，博士生導師。國家杰出青年科學基金獲得者，國家“萬人計劃”領軍人才、國家有突出貢獻中青年專家、國務院政府特殊津貼獲得者、百千萬人才工程國家級人選、中原學者；河南省科協(xié)副主席、河南省藥學會理事長、光譜學與光譜分析副主編、第十、十一屆藥典委員會委員。河南省新藥創(chuàng)制與藥物安全性評價協(xié)同創(chuàng)新中心主任，河南省有機功能分子與藥物創(chuàng)新重點實驗室主任。主要從事化學合成及創(chuàng)新藥物的研究與開發(fā)，主持863項目、國家杰出青年科學基金項目、國家自然科學基金重點項目、973項目課題、國家自然科學基金面上項目等17項。研發(fā)的抗艾滋病1.1類新藥阿茲夫定（FNC）順利完成了Ｉ期和Ⅱ期臨床試驗，目前正提請?zhí)崆吧鲜校谎邪l(fā)的1.1類新藥阿茲夫定能夠用于抗新型冠狀病毒且臨床試驗效果顯著，獲得國家藥品監(jiān)督管理局治療新型冠狀病毒肺炎Ⅲ期臨床批件，目前國內外正就FNC治療新冠肺炎開展Ⅲ期臨床試驗。研發(fā)的治療腦梗塞1.1類新藥BZP已進入Ⅱ期臨床試驗；研發(fā)的抗肺癌1.1類新藥“哆系替尼”進入了Ｉ-Ⅱ期臨床試驗。出版《艾滋病的分子生物學及治療》等學術著作9部。在Nature, Sc" /> <link type="text/css" href="/_css/_system/system.css" rel="stylesheet"/> <link type="text/css" href="/_js/_portletPlugs/sudyNavi/css/sudyNav.css" rel="stylesheet" /> <link type="text/css" href="/_js/_portletPlugs/simpleNews/css/simplenews.css" rel="stylesheet" /> <link href="/_upload/tpl/05/6c/1388/template1388/css/base.css" rel="stylesheet"> <link 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style="text-indent:0.85cm;font-size:20px;line-height:1.75em;">?？耍┦?，教授，博士生導師。國家杰出青年科學基金獲得者，國家“萬人計劃”領軍人才、國家有突出貢獻中青年專家、國務院政府特殊津貼獲得者、百千萬人才工程國家級人選、中原學者；河南省科協(xié)副主席、河南省藥學會理事長、光譜學與光譜分析副主編、第十、十一屆藥典委員會委員。河南省新藥創(chuàng)制與藥物安全性評價協(xié)同創(chuàng)新中心主任，河南省有機功能分子與藥物創(chuàng)新重點實驗室主任。</span></p><p style="text-indent:0.85cm;line-height:1.75em;margin-bottom:0cm;"><a name="_GoBack"></a><span style="font-size:20px;line-height:1.75em;"> </span></p><p style="text-indent:0.85cm;line-height:1.75em;margin-bottom:0cm;"><span style="text-indent:0.85cm;font-size:20px;line-height:1.75em;"> 主要從事化學合成及創(chuàng)新藥物的研究與開發(fā)，主持</span><span style="text-indent:0.85cm;font-family:calibri, serif;font-size:20px;line-height:1.75em;">863</span><span style="text-indent:0.85cm;font-size:20px;line-height:1.75em;">項目、國家杰出青年科學基金項目、國家自然科學基金重點項目、</span><span style="text-indent:0.85cm;font-family:calibri, serif;font-size:20px;line-height:1.75em;">973</span><span style="text-indent:0.85cm;font-size:20px;line-height:1.75em;">項目課題、國家自然科學基金面上項目等</span><span style="text-indent:0.85cm;font-family:calibri, serif;font-size:20px;line-height:1.75em;">17</span><span style="text-indent:0.85cm;font-size:20px;line-height:1.75em;">項。研發(fā)的抗艾滋病</span><span style="text-indent:0.85cm;font-family:calibri, serif;font-size:20px;line-height:1.75em;">1.1</span><span style="text-indent:0.85cm;font-size:20px;line-height:1.75em;">類新藥阿茲夫定（</span><span style="text-indent:0.85cm;font-family:calibri, serif;font-size:20px;line-height:1.75em;">FNC</span><span style="text-indent:0.85cm;font-size:20px;line-height:1.75em;">）順利完成了</span><span style="text-indent:0.85cm;font-size:20px;line-height:1.75em;">Ｉ</span><span style="text-indent:0.85cm;font-size:20px;line-height:1.75em;">期和</span><span style="text-indent:0.85cm;font-size:20px;line-height:1.75em;">Ⅱ</span><span style="text-indent:0.85cm;font-size:20px;line-height:1.75em;">期臨床試驗，目前正提請?zhí)崆吧鲜校谎邪l(fā)的</span><span style="text-indent:0.85cm;font-family:calibri, serif;font-size:20px;line-height:1.75em;">1.1</span><span style="text-indent:0.85cm;font-size:20px;line-height:1.75em;">類新藥阿茲夫定能夠用于抗新型冠狀病毒且臨床試驗效果顯著，獲得國家藥品監(jiān)督管理局治療新型冠狀病毒肺炎Ⅲ期臨床批件，目前國內外正就</span><span style="text-indent:0.85cm;font-family:calibri, serif;font-size:20px;line-height:1.75em;">FNC</span><span style="text-indent:0.85cm;font-size:20px;line-height:1.75em;">治療新冠肺炎開展Ⅲ期臨床試驗。研發(fā)的治療腦梗死</span><span style="text-indent:0.85cm;font-family:calibri, serif;font-size:20px;line-height:1.75em;">1.1</span><span style="text-indent:0.85cm;font-size:20px;line-height:1.75em;">類新藥</span><span style="text-indent:0.85cm;font-family:calibri, serif;font-size:20px;line-height:1.75em;">BZP</span><span style="text-indent:0.85cm;font-size:20px;line-height:1.75em;">已進入</span><span style="text-indent:0.85cm;font-size:20px;line-height:1.75em;">Ⅱ</span><span style="text-indent:0.85cm;font-size:20px;line-height:1.75em;">期臨床試驗；研發(fā)的抗肺癌</span><span style="text-indent:0.85cm;font-family:calibri, serif;font-size:20px;line-height:1.75em;">1.1</span><span style="text-indent:0.85cm;font-size:20px;line-height:1.75em;">類新藥“哆系替尼”進入了Ｉ</span><span style="text-indent:0.85cm;font-family:calibri, serif;font-size:20px;line-height:1.75em;">-Ⅱ</span><span style="text-indent:0.85cm;font-size:20px;line-height:1.75em;">期臨床試驗。出版《艾滋病的分子生物學及治療》等學術著作</span><span style="text-indent:0.85cm;font-family:calibri, serif;font-size:20px;line-height:1.75em;">9</span><span style="text-indent:0.85cm;font-size:20px;line-height:1.75em;">部。在</span><span style="text-indent:0.85cm;font-family:calibri, serif;font-size:20px;line-height:1.75em;">Nature, Science, Chem. Rev., J. Med. Chem.</span><span style="text-indent:0.85cm;font-size:20px;line-height:1.75em;">等</span><span style="text-indent:0.85cm;font-family:calibri, serif;font-size:20px;line-height:1.75em;">SCI</span><span style="text-indent:0.85cm;font-size:20px;line-height:1.75em;">期刊發(fā)表論文</span><span style="text-indent:0.85cm;font-family:calibri, serif;font-size:20px;line-height:1.75em;">300</span><span style="text-indent:0.85cm;font-size:20px;line-height:1.75em;">余篇，被他引</span><span style="text-indent:0.85cm;font-family:calibri, serif;font-size:20px;line-height:1.75em;">6000</span><span style="text-indent:0.85cm;font-size:20px;line-height:1.75em;">余次；獲中國發(fā)明專利</span><span style="text-indent:0.85cm;font-family:calibri, serif;font-size:20px;line-height:1.75em;">33</span><span style="text-indent:0.85cm;font-size:20px;line-height:1.75em;">件，美國發(fā)明專利</span><span style="text-indent:0.85cm;font-family:calibri, serif;font-size:20px;line-height:1.75em;">5</span><span style="text-indent:0.85cm;font-size:20px;line-height:1.75em;">件，歐洲專利</span><span style="text-indent:0.85cm;font-family:calibri, serif;font-size:20px;line-height:1.75em;">2</span><span style="text-indent:0.85cm;font-size:20px;line-height:1.75em;">件。獲得“全國創(chuàng)新爭先獎”、“中國專利金獎”、“國家自然科學二等獎”、“國家科技進步二等獎”、“河南省杰出貢獻獎”各</span><span style="text-indent:0.85cm;font-family:calibri, serif;font-size:20px;line-height:1.75em;">1</span><span style="text-indent:0.85cm;font-size:20px;line-height:1.75em;">項，“河南省科技進步一等獎”</span><span style="text-indent:0.85cm;font-family:calibri, serif;font-size:20px;line-height:1.75em;">2</span><span style="text-indent:0.85cm;font-size:20px;line-height:1.75em;">項。</span></p><p><br /></p></div></article> </div> <div class="pttp5z5" id="bdshare"> <div id="35prl3z" class="bdsharebuttonbox"><a href="javascript:void(0)" onClick="return false;" data-cmd="more" target="_blank;"></a><a href="javascript:void(0)" class="bds_qzone" data-cmd="qzone" title="分享到QQ空間"></a><a 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