個人簡介：

申聰聰，1989出生，河南洛陽人，博士，講師，

E-mail：shencongcong@htu.edu.cn

教育經(jīng)歷：

2008.09—2012.06   商丘師范學(xué)院   化學(xué)   理學(xué)學(xué)士

2012.09—2015.06   中南大學(xué)       分析化學(xué)   理學(xué)碩士

2015.09—2018.11   中南大學(xué)      分析化學(xué)    理學(xué)博士

主講課程：

分析化學(xué)、儀器分析、分析化學(xué)實驗、儀器分析實驗、藥物化學(xué)實驗等。

研究領(lǐng)域與方向：

納米新材料的合成，熒光納米探針的設(shè)計及生物成像；

新型電化學(xué)生物傳感體系的構(gòu)建，并用于體內(nèi)特定酶、糖蛋白、循環(huán)腫瘤細胞等癌癥標志物的檢測。

主持的科研項目：

1、河南省科技攻關(guān)項目：新型循環(huán)腫瘤細胞（CTC）電化學(xué)傳感體系的構(gòu)建及其在臨床早篩液體活檢中的應(yīng)用（10.00萬，項目編號：202102310139，2020.1-2021.12，在研）

2、河南師范大學(xué)博士科研啟動費支持課題：基于DNA產(chǎn)生電流技術(shù)構(gòu)建電化學(xué)細胞傳感器用于乳腺癌循環(huán)腫瘤細胞的檢測（8.00萬，2020.1-2022.12，在研）

3、河南師范大學(xué)國家級青年科學(xué)基金培育項目（4.00萬，在研）

4、湖南省博士研究生科研創(chuàng)新項目：基于上轉(zhuǎn)換納米顆粒光解藥物緩釋用于乳腺癌治療（3.00萬，項目編號：CX2016B039），已結(jié)題。

代表性成果：

<文章>

[1] Congcong Shen, Shuping Liu, Xiaoqing Li, and Minghui Yang*. Electrochemical Detection of Circulating Tumor Cells Based on DNA Generated Electrochemical Current and Rolling Circle Amplification. Analytical Chemistry, 2019, (91): 11614-11619. (IF=6.042)

[2] Congcong Shen, Ke Zeng, Junjun Luo, Xiaoqing Li, Minghui Yang*, and Avraham Rasooly*. Self-Assembled DNA Generated Electric Current Biosensor for HER2 Analysis [J]. Analytical Chemistry, 2017, 89(19): 10264-10269. (IF=6.042)

[3] Congcong Shen, Xiaodong Xia, Shengqiang Hu, Minghui Yang, and Jianxiu Wang. Silver nanoclusters-based fluorescence assay of protein kinase activity and its inhibitors. Analytical Chemistry, 2015, (87): 693-698. (IF=6.042)

[4] Congcong Shen, Xiangzhi Li, Avraham Rasooly, Linyan Guo, Kaina Zhang, Minghui Yang. A Single Electrochemical Biosensor for Detecting the Activity of Both Protein Kinase and Alkaline Phosphatase Based on Phosphate Ions Induced Deposition of Redox Precipitates. Biosensors and Bioelectronics, 2016, (85), 220-225. (IF=7.476)

[5] Congcong Shen^#, Juan Su^#, Xiangzhi Li, Junjun Luo, Minghui Yang. Electrochemical sensing platform based on Pd-Au bimetallic clusters for non-enzymatic detection of glucose. Sensors and Actuators, B chemical, 2015，(209): 695-700. (IF=5.667)

[6] Congcong Shen^#, Kaina Zhang^#, Nanxing Gao, Shijiong Wei, Guimei Liu, Yuanlin Chai, Minghui Yang*. Dual Modes of Colorimetric and Electrochemical Sensor for Detecting the Activity of Protein Kinase Based on Silver Enhancement Signal Amplification. Microchimica Acta. 2016 183:2933–2939 (IF=5.705）

[7] Congcong Shen^#, Shuping Liu^#, Xiaoqing Li, Dan Zhao, Minghui Yang*，Immunoelectrochemical detection of HER2 with gold nanoparticle-based rolling circle amplification. Microchim Acta. 2018 185:574-581 (IF=5.705）

[8] 申聰聰，陽明輝。蛋白激酶活性及抑制性檢測研究進展，化學(xué)傳感器。2015, 35 (1):49-57

[9] Xiaoqing Li, Congcong Shen, Minghui Yang,*and Avraham Rasooly*, Polycytosine DNA Electric-Current-Generated Immunosensor for Electrochemical Detection of Human Epidermal Growth Factor Receptor 2 (HER2). Analytical Chemistry, 2018, 90(7): 4764-4769. (IF=6.042)

[10] Lanshuang Hu, Shengqiang Hu, Linyan Guo, Congcong Shen, Minghui Yang,*and Avraham Rasooly*. DNA Generated Electric Current Biosensor. Analytical Chemistry, 2017, 89(4): 2547-2552. (IF=6.042)

[11] Yuxin Li, Congcong Shen, Xiaoqing Li, Minghui Yang*, and Chunshen Shao*. Hydroxyapatite nanoparticle based fluorometic determination and imaging of cysteine and homocysteine in living cells. Microchim Acta, 2018, 185(5):271-278. (IF=5.705）

[12] Kaina Zhang, Ke Zeng, Congcong Shen, Shiyu Tian, Minghui Yang*, Determination of protein kinase A activity and inhibition by using hydroxyapatite nanoparticles as a fluorescent probe. Microchim Acta, 2018, 185(4):225-232. (IF=5.705）

[13] Yuxin Li, Xiaoqing Li, Dan Wang, Congcong Shen, Minghui Yang, Hydroxyaptite nanoparticle based fluorometric turn-on determination of dipicolinic acid, a biomarker of bacterial spores. Microchim Acta, 2018 185: 2978-2982. (IF=5.705）

[14] Ke Zeng, Shiyu Tian, Zixiao Wang, Congcong Shen, Junjun Luo, Minghui Yang, You-Nian Liu, An ELISA for the determination of human IgG based on the formation of a colored iron(II) complex and photometric or visual read-out. Microchim Acta, 2017 184: 2791-2796. (IF=5.705）

[15] Luo Junjun, Avraham Rasooly,Wang Liqiang, Zeng Ke, Shen Congcong, Minghui Yang. Fluorescent turn-on determination of the activity of peptidases using peptide templated gold nanoclusters. Microchimica Acta, 2016,183(2): 605-610. (IF=5.705）

[16] Songbai Zhang, Xia Hu, Hongen Geng, Meixin Huang, Yangqing Qiu, Congcong Shen, Shuo Wang, Guangyu Shen, Minghui Yang, A highly sensitive and signal –on electrochemical aptasensor based on restriction endonuclease induced background elimination. Journal of the Electrochemical Society. 2016 163(8): B411-B416. (IF=3.48)

[17] Qingjun Guo, Xiangzhi Li , Congcong Shen ,Song bai Zhang, Haizhi Qi, Ting Li, Minghui Yang. Electrochemical immunoassay for the protein biomarker mucin 1 and for MCF-7 cancer cells based on signal enhancement by silver nanoclusters. Microchim Acta, 2015,182(7-8):1483-1489. (IF=5.705）

[18] Miao Zhou, Zhifang Sun, Congcong Shen, Zhengyuan Li, Yi Zhang , Minghui Yang. Application of hydrogel prepared from ferrocene functionalized amino acid in the design of novel electrochemical immunosensing platform. Biosensors and Bioelectronics, 2013, (49): 243-248. (IF=7.476)

<專利>

[1] 陽明輝，申聰聰，一種測定蛋白激酶活性的方法和蛋白激酶抑制劑活性的方法，已授權(quán)，專利號：ZL 201610058928.4

[2] 陽明輝， 申聰聰，張凱娜，一種基于比色法或電化學(xué)法測定蛋白激酶PKA的活性的方法，已授權(quán)，專利號：ZL 2016 1 0552292.9

[3] 陽明輝， 申聰聰，基于DNA產(chǎn)生電信號及自組裝放大信號的電化學(xué)適配體傳感器測定HER2的方法，已授權(quán)，專利號：ZL 2017 1 0091611.5

獲獎情況                                                                                       

（1）2016年獲得“中南大學(xué)拔尖博士校長獎學(xué)金”。

（2）2017年獲得中南大學(xué)優(yōu)秀碩士學(xué)位論文。

（3）2017年獲得湖南省優(yōu)秀碩士學(xué)位論文。