朱博，男，博士，副教授，碩士生導(dǎo)師。
入選博士后創(chuàng)新人才支持計(jì)劃（2017年）
河南省優(yōu)秀青年科學(xué)基金獲得者（2021年入選）
E-mail:zbtiantang@126.com；zhubo2019@htu.edu.cn
教育經(jīng)歷：
2005年9月—2009年7月，河南大學(xué)，藥學(xué)院，理學(xué)學(xué)士學(xué)位
2009年9月—2012年7月，河南大學(xué)，藥學(xué)院，醫(yī)學(xué)碩士學(xué)位，導(dǎo)師：江智勇教授、嚴(yán)琳教授
2013年9月—2016年7月，河南大學(xué)，化學(xué)化工學(xué)院，理學(xué)博士學(xué)位，導(dǎo)師：江智勇教授
工作經(jīng)歷：
2012年8月—2013年8月，漯河醫(yī)學(xué)高等?？茖W(xué)校 輔導(dǎo)員
2017年4月—2019年6月，河南師范大學(xué)，化學(xué)化工學(xué)院，師資博士后，合作導(dǎo)師：?？?biāo)教授
2019年6月—至今，河南師范大學(xué)，化學(xué)化工學(xué)院，副教授
研究領(lǐng)域與興趣：
1. 不對(duì)稱催化合成
2. 抗腫瘤、抗抑郁藥物合成
近年來主持的主要科研項(xiàng)目：
河南省自然科學(xué)基金-優(yōu)青，2021年，在研，主持
國家自然科學(xué)基金（81903465）：手性含氟東莨菪堿類似物的設(shè)計(jì)、合成及其抗抑郁活性研究，主持。
博士后創(chuàng)新人才支持計(jì)劃（BX201700071）：藥物分子中手性仲醇構(gòu)建新手段，主持。
博士后面上基金（2017M622348）：構(gòu)建γ-官能團(tuán)化非相鄰手性仲醇的不對(duì)稱質(zhì)子化反應(yīng)，主持。
代表性論文：
（20）Li, L.; Zhu, B.*; Fan, H.; Jiang, Z.; Chang, J.* Direct organocatalytic asymmetric Michael reaction of fluorine hemiaminal-type nucleophile to 4-nitro-5-styrylisoxazoles. Organic Chemistry Frontiers 2020, 7, 1343–1348.
（19）Xu, X.; He, Y.; Zhou, J.; Li, X.; Zhu, B.*; Chang, J.* Organocatalytic Asymmetric Michael Addition of Pyrazol-5-ones to β?Trifluoromethyl-α,β-unsaturated Ketones: Stereocontrolled Construction of Vicinal Quaternary and Tertiary Stereocenters. J. Org. Chem.2020, 85, 574?584
（18）Lu, B.; Xin, S.; Zhu, B.*; Chang, J.* Enantioselective Conjugate Addition–Protonation of 5H-Oxazol-4-ones and 5-Methylene 1,3-oxazolidine-2,4-diones: 2,2'-Biphenol-Induced Diastereoselectivity Switch. Chin. J. Chem. 2019, 37, 689-694. (invited)
（17）Zhu, B.; Lu, B.; Zhang, H.; Xu, X.; Jiang, Z.*; Chang, J.* Phase-Transfer-Catalyzed, Enantioselective Vinylogous Conjugate Addition?Cyclization of Olefinic Azlactones To Access Multifunctionalized Chiral Cyclohexenones. Org. Lett. 2019, 21,3271-3275.
（16）Chai, G.; Zhu, B.; Chang, J.* Synthesis and Application of Substituted 1,16-Dihydroxytetraphenylenes in Catalytic symmetric Allylboration of Ketones. J. Org. Chem. 2019, 84, 120–127.
（15）Xia, X.; Zhu, Q.; Wang, J.; Chen, J.; Cao, W.; Zhu, B.*; Wu, X.* Direct Asymmetric Vinylogous Mannich Addition of 3,5-Disubstituted-4-nitroisoxazoles to Isatin-Derived Imines Catalyzed by a Bifunctional Phase-Transfer-Catalyst. J. Org. Chem. 2018, 83, 14617–14625.
（14）Zhu, B.; Li, F.; Lu, B.; Chang, J.*; Jiang, Z.* Organocatalytic Enantioselective Vinylogous Aldol Reaction of 5-Alkyl-4-Nitroisoxazoles to Paraformaldehyde. J. Org. Chem. 2018, 83, 11350–11358.
（13）Zhu, B.; Lee, R.; Yin, Y.; Li, F.; Coote, M.*; Jiang, Z.* Enantioselective Vinylogous Amination of 5-Alkyl-4-nitroisoxazoles with a Dipeptide-Based Guanidinium Phase-Transfer Catalyst. Org. Lett. 2018, 20, 429?432.
（12）Li, S.; Zhu, B.(共一); Lee, R.; Qiao, B.; Jiang, Z.* Visible light-induced selective aerobic oxidative transposition of vinyl halides using a tetrahalogenoferrate(III) complex catalyst. Organic Chemistry Frontiers 2018, 5, 380?385.
（11）Zhu, B.; Qiu, S.; Li, J.; Coote, M. L.; Lee, R.; Jiang, Z.* Asymmetric [4+2] annulation of 5H-thiazol-4-ones with a chiral dipeptide-based Br?nsted base catalyst. Chem. Sci. 2016, 7, 6060–6067.
（10）Zhu, B.; Lee, R.; Li, J.; Ye, X.; Hong, S.-N.; Qiu, S.; Coote, M. L.; Jiang, Z.* Chemoselective Switch in Asymmetric Organocatalysis of 5H-oxazol-4-ones and N-Itaconimides towards Tandem Conjugate Addition?Protonation or [4+2] Cycloaddition. Angew. Chem. Int. Ed. 2016, 55, 1299?1303.
（9）Zhu, B.; Zhang, W.; Lee, R.; Han, Z.; Yang, W.; Tan, D.; Huang, K.-W.; Jiang, Z.* Direct Asymmetric Vinylogous Aldol Reaction of Allyl Ketones with Isatins: Divergent Synthesis of 3-Hydroxy-2-Oxindole Derivatives. Angew. Chem. Int. Ed. 2013, 52, 6666–6670 (Selected as the inside back cover picture of Angewandte Chemie) (Highlighted by Synfacts 2013, 9, 0784–0784; Contributors: Benjamin List, Mattia Riccardo Monaco).
（8）Zhu, B.; Yan, L.; Pan, Y.; Lee, R.; Liu, H.; Han, Z.; Huang, K.-W.; Tan. C.-H.; Jiang, Z. Lewis Base Catalyzed Enantioselective Allylic Hydroxylation of Morita-Baylis-Hillman Carbonates with Water. J. Org. Chem. 2011, 76, 6894?6900.
（14）Zhao, X.; Zhu, B.; Jiang, Z.* Acyclic Amino Acid-Based Bifunctional Chiral Tertiary Amines, Quaternary Ammoniums and Iminophosphoranes as Organocatalysts. Synlett 2015, 26, 2216?2230. (Invited Account).
（7）Tong, G.; Zhu, B.; Lee, R.; Yang, W.; Tan, D.; Yang, C.; Han, Z.; Yan, L.; Huang, K.-W.; Jiang, Z.* Highly Enantio- and Diastereoselective Allylic Alkylation of Morita-Baylis-Hillman Carbonates with Allyl Ketones. J. Org. Chem. 2013, 78, 5067–5072.
（6）Qiu, S.; Lee, R.; Zhu, B.; Coote, M. L.; Zhao, X.; Jiang, Z.* Highly Enantio- and Diastereoselective [4 + 2] Cycloaddition of 5H oxazol-4-ones with N Maleimides. J. Org. Chem. 2016, 81, 8061?8069.
（5）Yan, L.; Han, Z.; Zhu, B.; Yang, C.; Tan, C.-H.; Jiang, Z.* Asymmetric Alylic Alkylation of Morita-Baylis-Hillman Carbonates with α-Fluoro-β-Keto Esters. Beilstein J. Org. Chem. 2013, 9, 1853–1857.
（4）Li, J.; Qiu, S.; Ye, X.; Zhu, B.; Liu, H,; Jiang, Z.* Dipeptide-Based Chiral Tertiary Amine-Catalyzed Asymmetric Conjugate Addition Reactions of 5H-Thiazol/Oxazol-4-Ones. J. Org. Chem. 2016, 81, 11916?11923.
（3）Jiang, Z.; Bai, X.; Chen, W.; Zhang, G.; Zhu, B.; Jiang, Z.* Organocatalytic Enantioselective Vinylogous Aldol Reaction of Allyl Ketones to Activated Acyclic Ketones. Org. Lett. 2016, 18, 260?263.
（2）Yang, C.; Chen, W.; Yang, W.; Zhu, B.; Yan, L.; Tan, C.-H.; Jiang, Z.* Bicyclic-Guanidine-Catalyzed Asymmetric Michael Addition of 3-Substituted Oxindoles to 2-Cyclopentenone. Chem. Asian J. 2013, 8, 2960?2964.
（1）Yang, W.; Wei, X.; Pan, Y.; Lee, R.; Zhu, B.; Liu, H.; Yan, L.; Huang, K.-W.; Jiang, Z.;* Tan, C.-H. Highly Enantio- and Diastereoselective Synthesis of β-Methyl-γ- Monofluoromethyl-Substituted Alcohols. Chem. Eur. J. 2011, 17, 8066?8070. (VIP paper)