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          劉丙賢

          時(shí)間:2019-07-08瀏覽:8184設(shè)置



          個(gè)人簡介:


          劉丙賢,男,博士,副教授,中共黨員

          電話:15737352811

          E-mail: liubx1120@163.com;liubingxian@htu.edu.cn


          教育經(jīng)歷:
          2006/09-2010/06
          ,山東大學(xué),化學(xué)與化工學(xué)院,學(xué)士

          2010/09-2015/06,南開大學(xué),化學(xué)學(xué)院化學(xué)系,博士,導(dǎo)師:王佰全教授

          工作經(jīng)歷:

          2015.07-2016.07,江蘇豪森藥業(yè)集團(tuán)有限公司豪森研究院,化學(xué)開發(fā)員

          2016/8-2020/5,河南師范大學(xué),化學(xué)化工學(xué)院,講師

          2020/6至今,河南師范大學(xué),化學(xué)化工學(xué)院,副教授

          研究領(lǐng)域與興趣:

          1、基于碳?xì)滏I活化轉(zhuǎn)化的有機(jī)合成方法學(xué)及其在藥物合成中的應(yīng)用開發(fā)

          2、基于廉價(jià)金屬的不對(duì)稱碳?xì)滏I活化

          近年來主持的主要科研項(xiàng)目:
          1
          、國家自然科學(xué)基金項(xiàng)目(21801066):基于錳催化C-H鍵活化環(huán)化串聯(lián)反應(yīng)的結(jié)構(gòu)多樣性吲哚衍生物合成方法研究

          2、河南省高等學(xué)校重點(diǎn)科研項(xiàng)目(19A150028),錳催化的碳?xì)滏I活化環(huán)化串聯(lián)反應(yīng)研究

          3、中國博士后科學(xué)基金特別資助(2021T140183),α-甲基碳(硅)手性中心的不對(duì)稱構(gòu)建新方法

          代表性論文:

          16. Zhenzhen Dong,? Pengfei Li,? Xingwei Li, and Bingxian Liu*, Rh(III)-Catalyzed Diverse C—H Functionalization of Iminopyridinium Ylides, Chin. J. Chem., 2021, 39, 2489.

          15. Bingxian Liu,* Pengfei Xie, Jie Zhao, Juanjuan Wang, Manman Wang, Yuqin Jiang, Junbiao Chang,* Xingwei Li*, Rhodium-Catalyzed Enantioselective Synthesis of b-Amino Alcohols via Desymmetrization of gem-Dimethyl Groups, Angew. Chem. Int. Ed., 2021, 60, 8396.

          14. Bingxian Liu,* Lingyun Yang, Pengfei Li, Fen Wang, Xingwei Li*, Recent advances in transition metal-catalyzed olefifinic CH functionalization, Org. Chem. Front., 2021, 81085.

          13. Yuqin Jiang, Pengfei Li, Jie Zhao, Bingxian Liu,*Xingwei Li*, Iodonium Ylides as Carbene Precursors in Rh(III)-Catalyzed C?Activation, Org. Lett., 2020, 22, 7475.

          12. Yuqin Jiang, Pengfei Li, Juanjuan Wang, Jie Zhao, Yang Li, Yawen Zhang, Junbiao Chang*, Bingxian Liu*, Xingwei Li*, Rh(III)-Catalyzed Coupling of Acrylic Acids and Ynenones via Olefinic C-H Activation and Michael Addition, Org. Lett., 2020, 22, 438.

          11. Bingxian Liu*,Yin Yuan,a Panjie Hu, Guangfan Zheng, Dachang Bai, Junbiao Chang*, Xingwei Li*, Mn(I)-Catalyzed nucleophilic addition/ring expansion via C–H activation and C-C cleavage, Chem. Commun., 2019, 55, 10764.

          10. Bingxian Liu, Jie Li, Panjie Hu, Xukai Zhou, Dachang Bai, Xingwei Li*, Divergent Annulative C?C Coupling of Indoles Initiated by Manganese-Catalyzed C?H Activation, ACS Catal., 2018, 8, 9463.

          9. Panjie Hu, Ying Zhang, Youwei Xu, Shuang Yang, BingxianLiu*, Xingwei Li*, Construction of (Dihydro)naphtho[1,8-bc]pyrans via Rh(III)-Catalyzed Twofold C?H Activation of Benzoylacetonitriles, Org. Lett., 2018, 20, 2160.

          8. Panjie Hu, Ying Zhang, Bingxian Liu*, Xingwei Li*, Facile construction of hydrogenated azepino [3,2,1-hi]indoles by Rh(III)-catalyzed C–H activation/[5+2] annulation of N-cyanoacetylindolines with sulfoxonium ylides, Org. Chem. Front., 2018, 5, 3263.

          7. Miaomiao Tian, Bingxian Liu, Jiaqiong Sun, Xingwei Li*, Rh(III)-Catalyzed C-C Coupling of Diverse Arenes and 4-Acyl-1-sulfonyltriazoles via C-H Activation, Org. Lett., 2018, 20, 4946.

          6. Bingxian Liu, Panjie Hu, Xukai Zhou, Dachang Bai, Junbiao Chang,* Xingwei Li*, Cp*Rh(III)-Catalyzed Mild Addition of C(sp3)?H Bonds to α,β Unsaturated Aldehydes and Ketones, Org. Lett., 2017, 19, 2086.

          5. Bingxian Liu, Panjie Hu, Ying Zhang, Yunyun Li, Dachang Bai, Xingwei Li*, Rh(III)-Catalyzed Diastereodivergent Spiroannulation of Cyclic Imines with Activated Alkenes, Org. Lett., 2017, 19, 5402.

          4. Lingheng Kong, Bingxian Liu, Xukai Zhou, Fen Wang, Xingwei Li*, Rhodium(III)-catalyzed regio- and stereoselective benzylic α-fluoroalkenylation with gem-difluorostyrenes, Chem. Commun., 2017, 53, 10326.

          3. Bingxian Liu, Bin Li, Baiquan Wang*, Ru(II)-catalyzed amidation reactions of 8-methylquinolines with azides via C(sp3)–H activation, Chem. Commun., 2015, 51, 16334 .

          2. Bingxian Liu, Tao Zhou, Bin Li, Shansheng Xu, Haibin Song, Baiquan Wang*, Rhodium(III)-Catalyzed Alkenylation Reactions of 8-Methylquinolines with Alkynes by C(sp3)-H Activation, Angew. Chem. Int. Ed., 2014, 53, 4191.

          1. Xing Tan, Bingxian Liu, Xiangyu Li, Bin Li, Shansheng Xu, Haibin Song, Baiquan Wang*, Rhodium-Catalyzed Cascade Oxidative Annulation Leading to Substituted Naphtho[1,8-bc]pyrans by Sequential Cleavage of C(sp2)–H/C(sp3)–H and C(sp2)–H/O–H Bonds, J. Am. Chem. Soc., 2012, 134, 16163.




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