何艷，女，1988年1月出生，博士，2009年畢業(yè)于河南師范大學(xué)化學(xué)化工學(xué)院并獲得理學(xué)學(xué)士學(xué)位；2009-2012年在河南師范大學(xué)化學(xué)化工學(xué)院攻讀有機(jī)化學(xué)碩士學(xué)位，在導(dǎo)師范學(xué)森教授的指導(dǎo)下從事有機(jī)合成方法學(xué)的研究，2012年7月獲得理學(xué)碩士學(xué)位；2012-2015年在河南師范大學(xué)環(huán)境學(xué)院攻讀環(huán)境科學(xué)綠色合成方向的博士學(xué)位，在導(dǎo)師范學(xué)森教授的指導(dǎo)下主要從事基于官能團(tuán)化聯(lián)烯多樣反應(yīng)性能的綠色合成方法學(xué)研究，2015年12月獲得工學(xué)博士學(xué)位。2015年12月進(jìn)入河南師范大學(xué)環(huán)境學(xué)院工作。主持國家自然科學(xué)基金項(xiàng)目一項(xiàng)，河南省科技攻關(guān)計(jì)劃項(xiàng)目一項(xiàng)，參與國家自然科學(xué)基金項(xiàng)目三項(xiàng)。在Green Chem., Chem. Comm., Org. Lett., J. Org. Chem., Chem. Asian J.,等SCI期刊發(fā)表論文20余篇。
綠色化學(xué)；有機(jī)合成化學(xué)；核苷衍生物的合成及性能
1. 城市污水生化處理出水中有機(jī)物對循環(huán)冷卻水系統(tǒng)中礦物結(jié)垢、微生物結(jié)垢和金屬腐蝕過程的作用及機(jī)理，國家自然科學(xué)基金，23萬，主持。
2. 城市污水生化處理出水中有機(jī)物對冷卻水系統(tǒng)結(jié)垢和腐蝕的影響，河南省博士后一等資助，10萬，主持。
3. 選擇性同步去除二級出水中硝酸鹽/磷酸鹽復(fù)合功能樹脂制備及機(jī)理，河南省教育廳重點(diǎn)研究項(xiàng)目，3萬，主持。
4. 3D多孔Cu/Pd雙金屬電極制備及城市污水電催化深度脫硝研究，河南師范大學(xué)青年科學(xué)基金項(xiàng)目，6萬，主持。
代表性論文：
1. Fang Wang, Yan He*, Miaomiao Tian, Xinying Zhang, Xuesen Fan*. Synthesis of α-formylated N-heterocycles and their 1,1-diacetates through the cascade reactions of inactivated cyclic amines featured with an oxidative ring contraction. Org. Lett., 2018, 20, 864-867.
2. Yan He*, Fang Wang, Xinying Zhang, Xuesen Fan*. C(sp3)?H dehydrogenation and C(sp2)?H alkoxycarbonylation of inactivated cyclic amines towards functionalized N-heterocycles. Chem. Commun., 2017, 53, 4002-4005.
3. Yan He, Ningning Zhao, Liqi Qiu, Xinying Zhang*, Xuesen Fan*. Regio- and chemoselective mono- and bisnitration of 8-aminoquinoline amides with Fe(NO3)3·9H2O as promoter and nitro source. Org. Lett., 2016, 18, 6054-6057.
4.Xuesen Fan*, Yan He, Xinying Zhang, Jianji Wang. Sustainable and selective synthesis of 3,4-dihydro quinolizin-2-one and quinolizin-2-one derivatives via the reactions of penta-3,4-dien-2-ones. Green Chemistry, 2014, 16, 1393-1398.
5.Yan He, Xinying Zhang*, Liangyan Cui, Jianji Wang, Xuesen Fan*. Catalyst-free synthesis of diversely substituted 6H-benzo[c]chromenes and 6H-benzo[c]chromen-
6-ones in aqueous media under MWI. Green Chemistry, 2012, 14, 3429-3435.
6. Xuesen Fan*, Yan He, Liangyan Cui, Xinying Zhang, Jianji Wang. Tandem reaction of 1,2-allenic ketone with α-halo ketone or α-halo ester in water: an efficient and sustainable synthesis of 1,3,4'-tricarbonyl compounds. Green Chemistry, 2011, 13, 3218-3223.
7.Yan He, Xinying Zhang*, and Xuesen Fan*.Synthesis of diversely substituted 2-(furan-3-yl)acetates from allenols through cascade carbonylations. Chemical Communications, 2015, 51,16263-16266.
8.Yan He, Xinying Zhang,* and Xuesen Fan*.One-pot cascade reactions of 1-arylpenta- 3,4-dien-2-ones leading to 2-arylphenols and dibenzopyroanones. Chemical Communications, 2014, 50, 14968-14970.
9.Yan He, Xinying Zhang and Xuesen Fan*.Synthesis of naphthalene amino esters and arylnaphthalene lactone lignans through tandem reactions of 2-alkynylbenzonitriles. Chemical Communications, 2014, 50, 5641-5643.
10.Miaomiao Tian, Yan He, Xinying Zhang,* and Xuesen Fan*,Synthesis of Pyrazolo [5,1?a]isoindoles and Pyrazolo[5,1?a]isoindole-3-carboxamides through One-Pot Cascade Reactions of 1-(2-Bromophenyl)buta-2,3-dien-1-ones with Isocyanide and Hydrazine or Acetohydrazide. Journal of Organic Chemistry, 2015, 80, 7447-7455.
11.Yan He, Shenghai Guo, Xinying Zhang, and Xuesen Fan*.Zinc-mediated one-pot tandem reaction of nitriles with propargyl bromides: an easy access to 3-alkynylpyri dines and their applications. Journal of Organic Chemistry, 2014, 79, 10611.
12.Yan He, Xinying Zhang, Nana Shen, Xuesen Fan*. Tunable synthesis of 3-acyl-2- naphthols and 3-substituted isocoumarins via Jones reagent promoted cascade reacti ons of 2-(4-hydroxy-but-1-ynyl) benzaldehydes. Journal of Organic Chemistry, 2013, 78, 10178-10191.
13.Yan He, Xinying Zhang*, Liangyan Cui, Xuesen Fan*. Iodine-initiated domino reaction of hepta-1,2- dien-6-yn-4-ols and br?nsted acid promoted cyclization of hepta-1,2,6-trien-4-ols leading to functionalized benzenes. Chemistry-An Asian Journal, 2013, 8, 717-722.
14.Yan He, Miaomiao Tian, Xinying Zhang, and Xuesen Fan*，Synthesis of 4-Oxo-
but-2-enals through tBuONO and TEMPO-Promoted Cascade Reactions of Homo
allylic Alcohols，Asian Journal of Organic Chemistry, 2016, DOI: 10.1002/ajoc.201600312
15.Yan He, Xinying Zhang, and Xuesen Fan*，Synthesis of Aminonaphthopyranones and Aminonaphthochromenones by Blaise-Reaction-Initiated Cascade Procedures，Asian Journal of Organic Chemistry, 2014, 3, 1284 – 1291。
16.Xuesen Fan*, Yan He, Liangyan Cui, Shenghai Guo, Jianji Wang, Xinying Zhang*. Tandem reactions leading to benzo[c]chromen-6-ones and 3-substituted isocoumarins. European Journal of Organic Chemistry, 2012 (4), 673-677.
17.Yan He, Nana Shen, Xuesen Fan*, Xinying Zhang. Synthesis of β-fluoroenones and their reductive rearrangement in aqueous media. Tetrahedron, 2013, 69, 8818-8823.
18.Xuesen Fan*, Yan He, Xinying Zhang, Shenghai Guo. Synthesis of heteroaryl ketones via tandem reaction of 1,1-dibromoethenes. Tetrahedron, 2011, 67, 6369-6374.
19.Yan He, Shenghai Guo, Xinying Zhang,* Chenhao Guo, and Xuesen Fan*. Synthesis of Dibenzo[b,d]furans through One-pot Cascade Reactions of 1-Arylpenta-3,4-dien-2- ones with Activated Ketones. Tetrahedron Letters, 2015, 56, 1513-1516.
20.Yan He, Shenghai Guo, Xuesen Fan*, Chenhao Guo, Xinying Zhang*.One-pot synthesis of 12H-benzo[b]xanthen-12-ones and naphtha[2,3-b]furans from non-naphthalene substrates. Tetrahedron Letters. 2014, 55, 4747–4752.
21.Xuesen Fan*, Yan He, Yangyang Wang, Zaikun Xue, Xinying Zhang, Jianji Wang. A novel and practical synthesis of 2-benzoyl benzothiazoles and 2-benzylbenzothia zoles. Tetrahedron Letters, 2011, 52, 899-902.
22.Xuesen Fan*, Yan He, Shenghai Guo, Xinying Zhang. RuCl3?3H2O catalyzed tandem reaction of alkynylbromides with 2-aminothiophenols in water: a convenient synthesis of 2-benzoylbenzothiazoles. Australian Journal of Chemistry, 2011, 64, 1568-1573.
23.Yan He, Xinying Zhang, Nana Shen, Xuesen Fan*. Synthesis of α-fluoroketones and α-fluoroenones in aqueous media. Journal of Fluorine Chemistry, 2013, 156, 9-14.
專利成果：
(1) 范學(xué)森，張新迎，李曉嚴(yán)，王洋洋，徐海云，郭勝海，何艷，具有抗HIV活性的5-取代嘧啶核苷-噻唑啉酮雜化體及其制備方法，2013.8.14，中國，ZL201210026427.X。
(2) 范學(xué)森，張新迎，何艷，郭勝海，田苗苗，一種吡唑并[5,1-a]異吲哚類化合物的合成方法，2015.9.23，中國，CN201510345540.8。
(3) 范學(xué)森，何艷，張新迎，郭勝海，田苗苗，一種吡唑并[5,1-a]異吲哚-3-甲酰胺類化合物的合成方法，2015.11.11，中國，CN201510345086.6。
(4) 范學(xué)森，張新迎，何艷，郭勝海，王園園，一種3-炔基吡啶類化合物的合成方法，2015.1.28，中國，CN201410515647.8。
(5) 張新迎，范學(xué)森，郭勝海，蔣盼盼，沈娜娜，何艷，李彬，具有抗寄生蟲活性的核苷-苯基丙烯酮雜化體及其制備方法和應(yīng)用，2015.4.8，中國，CN201410197474.X。
(6) 范學(xué)森，張新迎，馮東，王國利，王霞，郭勝海，王洋洋，何艷，賈雪菲，5-位缺電子烯基取代嘧啶碳環(huán)核苷及制備方法，2013.8.14，中國，CN201210026439.2。
(7) 張新迎，范學(xué)森，郭勝海，何艷，賈雪菲，崔良艷，方亮亮，5-位氫化苯并吡喃基取代嘧啶碳環(huán)核苷及制備方法，2013.8.14，中國，CN201210026464.0。
(8) 范學(xué)森，張新迎，馮東，王國利，曲瑩瑩，王洋洋，郭勝海，何艷，賈雪菲，5-甲?；奏ぬ辑h(huán)核苷及制備方法，2012.7.25，中國，CN201110463012.4。
(9) 范學(xué)森，張建瑞，張新迎，何艷，郭勝海，一種合成5-((E)-2-溴乙烯基)-2′-脫氧尿嘧啶核苷(溴呋啶)的方法，2012.5.2，中國，CN201110359183.2。